严芳 吴迪 卢寅

[摘要]目的：对比分析强脉冲光与点阵激光治疗面部皮肤光老化患者的临床疗效。方法：选择2015年1月-2020年1月笔者医院收治的83例面部皮肤光老化患者为研究对象，根据随机数字法将患者分为研究组（43例）和对照组（40例），研究组采用点阵激光治疗，对照组采用强脉冲光治疗，对比两组患者临床疗效、并发症发生率及美观满意度相关指标差异。结果：研究组临床疗效明显高于对照组（95.35% vs 80.00%）（P<0.05）;两组患者斑点、皱纹及纹理指标评分均显著降低，而研究组降低程度更显著（P<0.05）;研究组患者满意度高于对照组（97.67% vs 82.50%），治疗后并发症发生率显著低于对照组（P<0.05）。结论：强脉冲光与点阵激光均可有效治疗面部皮肤光老化，而点阵激光治疗临床疗效更佳，并发症发生率低，患者满意度高。

[关键词]点阵激光;强脉冲光;面部皮肤光老化;临床疗效;美观满意度

[中图分类号]R339.3+8    [文献标志码]A    [文章编号]1008-6455（2021）05-0097-04

Comparison and Analysis on Clinical Effect between Intense Pulsed Light and Fractional Laser in the Treatment of Photoaging of Facial Skin

YAN Fang1， WU Di2 ， LU Yin1

（1.Department of Dermatology， Central Hospital of Pukou District， Nanjing 210000， Jiangsu，China; 2. Department of Dermatology， Jiangsu Provincial People's Hospital， Nanjing 210000，Jiangsu，China）

Abstract： Objective  To compare and analyze the clinical efficacy between intense pulsed light and fractional laser in the treatment of photoaging of facial skin. Methods  83 patients with facial skin photoaging admitted in our hospital from January 2015 to January 2020 were selected as the research object， and the patients were divided into a study group （43 cases） and a control group （40 cases） according to the random number method. The patients in the study group were treated with fractional laser， and the control group was treated with intense pulsed light. The clinical efficacy， incidence of complications， and satisfaction with aesthetic between the two groups were compared. Results  The clinical efficacy of the study group was significantly higher than that of the control group （95.35% vs 80.00%） （P<0.05）. The scores in spots， wrinkles， and textures of the two groups significantly reduced， while the reduction of the study group was more significant （P<0.05）. The satisfaction of the patients in the study group was higher than that in the control group （97.67% vs 82.50%）， and the incidence of complications after treatment was significantly lower than that in the control group （P<0.05）. Conclusion  Both intense pulsed light and fractional laser can effectively treat photoaging of facial skin， while fractional laser has better clinical efficacy， lower incidence of complications， and higher satisfaction of patient.

Key words： fractional laser; intense pulsed light; photoaging of facial skin; clinical efficacy; satisfaction with aesthetic

皮膚老化是由于内源性或外源性的多种因素引起的较为复杂的衰老过程。内源性因素引起的皮肤老化是一种不可避免的自然过程;在外源性因素中，由日光、紫外线等引起的皮肤衰老过程称为光老化[1]。面部皮肤出现光老化，临床表现为色素增加、皱纹等，对患者的外貌产生一定的影响，病情严重者还有可能诱发皮肤癌、恶性肿瘤等[2]。临床上，对于面部皮肤光老化的治疗，通常以强脉冲光为主，可增加新生胶原的合成，同时对细胞外基质蛋白的合成具有促进作用，其疗效受广大患者肯定，然而其短期疗效不明显也一直是临床讨论的热点话题[3]。近年来，点阵激光应用于临床的相关研究也不断增多，应用于光老化中主要是通过一系列激光的作用下，使皮肤的真皮组织不受损并不断改善，为皮肤光老化治疗提供了方向与更多的可能性[4-5]。本研究通过对面部皮肤光老化患者的临床疗效及相关指标进行探究，分析点阵激光及强脉冲光对面部皮肤光老化患者疗效的影响因素，现将结果报道如下。……