观察奥氮平联合茴拉西坦治疗伴发精神行为症状的老年痴呆患者疗效及对生活质量的影响
2020-10-14苟玉娟
苟玉娟
【摘 要】目的: 对伴发精神行为症状的老年痴呆患者临床中采用奥氮平联合茴拉西坦治疗的整体效果进行观察。方法: 将2018年1月-2020年1月期间我院收治的80例伴患者采用入院奇偶数的方式平均分成两组,每组40例患者;其中常规组患者采用奥氮平治疗,而实验组采用联合茴拉西坦治疗,对比两种治疗方案对伴发精神行为症状的老年痴呆患者疗效及对生活质量的影响。结果: 根据治疗后指标表示:实验组( 联合茴拉西坦治疗)的总有效率为97.50%,常规组(奥氮平治疗)的总有效率为85.00%;且实验组患者的生活质量相较于常规组患者评分较高,精神行为症状评分较低;两组相关数据对比,组间差异明显,具有统计学意义(P<0.05);结论: 奥氮平联合茴拉西临床疗效显著,不仅可以改善老年痴呆患者的精神行为症状,同时也可以整体提高患者的生活质量。
【关键词】茴拉西坦;奥氮平;精神行为;老年痴呆;治疗总有效率;生活质量
Abstract Objective: To observe the effect of olanzapine combined with anisotham in the treatment of senile dementia patients with mental and behavioral symptoms. Methods :80 patients in our hospital were divided into two groups ,40 patients in each group, among which the routine group was treated with olanzapine, and the experimental group was treated with anisotham. The effect of the two treatment schemes on senile dementia patients with mental and behavioral symptoms and the effect on quality of life were compared. Results: A total effective rate of 97.50% in the experimental group and 85.00% in the routine group (olanzapine treatment), and a higher quality of life and lower mental and behavioral symptoms in the experimental group compared with the routine group (P<0.05). Conclusion: the clinical effect of olanzapine combined with fennelassie is remarkable, which can not only improve the mental and behavioral symptoms of senile dementia patients, but also improve the quality of life of patients as a whole.
Key Words anisotham; olanzapine; mental behavior; Alzheimers disease; total effective treatment; quality of life
【中圖分类号】R749.16【文献标识码】A【文章编号】1672-3783(2020)07-21--01
老年痴呆属于我院临床治疗中较为常见的一种神经系统退行性疾病,医学上又被称为阿尔茨海默病(AD),据相关流行病学资料表示,该疾病在85岁以上老年人中,患病率可达20%,需要相关人员给予重视。如果不及时采取有效的治疗措施对老年患者的病情进行控制,将会严重影响患者的日常生活质量,甚至出现道德伦理念缺乏的现象;临床中主要采取常规的抗精神异常药物进行治疗,比如:奥氮平,但是相关研究结果表示,其虽然具有一定的治疗效果,但是并不能改善患者的记忆障碍,需要进一步研究分析;本文将对伴发精神行为症状的老年痴呆患者临床中采用奥氮平联合茴拉西坦治疗的整体效果进行观察为临床治疗提供更多重要的参考依据,以下为具体研究内容。……
