厄贝沙坦在高血压性肾功能衰竭治疗中的应用价值分析
2021-09-10查晶
查晶



【摘要】目的:分析厄贝沙坦在高血压性肾功能衰竭治疗中的应用价值。方法:以86例高血压性肾功能衰竭患者为研究对象,在电脑随机方法下均分为对照组及研究组,其中对照组接受常规治疗(硝苯地平+美洛托尔),常规治疗基础上加用厄贝沙坦治疗,观察两组患者的疗效及肾功能转归情况。结果:治疗后,舒张压研究组为(78.3±4.0)mmHg,低于对照组的(85.9±5.2)mmHg,收缩压研究组为(129.7±8.5)mmHg,低于对照组的(144.6±8.3)mmHg,尿素氮研究组为(7.6±1.1)mmol/L,低于对照组的(10.8±1.7)mmol/L,肌酐研究组为(83.7±12.5)μmol/L,低于对照组的(109.7±18.2)μmol/L,肾小球滤过率为(112.0±9.5)mL/min,高于對照组的(87.6±5.4)mL/min,以上差异均具有统计学意义,P<0.05。结论:在高血压性肾功能衰竭患者的治疗中应用厄贝沙坦,可提高患者的治疗效果,更好的控制血压,改善患者肾功能,临床应用价值高。
【关键词】厄贝沙坦;高血压性肾功能衰竭;应用价值
【中图分类号】R652 【文献标识码】A 【文章编号】2026-5328(2021)05-033-02
[Abstract] Objective: To analyze the application value of Irbesartan in the treatment of hypertensive renal failure.Methods: a total of 86 patients with hypertensive renal failure were randomly pided into control group and study group under the computer random method. The control group received conventional treatment (nifedipine + melotor) and irbesartan on the basis of conventional treatment, and the efficacy and renal function outcome of the two groups were observed.Results:After treatment, the diastolic blood pressure group was (78.3±4.0) mmHg lower than the control group (85.9±5.2) mmHg, systolic blood pressure group was (129.7±8.5) mmHg lower than the control group (144.6±8.3) mmHg, urea nitrogen group was (7.6±1.1) mmol/L lower than the control group (10.8±1.7) mmol/L, and creatinine group was (83.7±12.5) mol/L lower than the control group (109.7±18.2) mol/L.The glomerular filtration rate was (112.0±9.5) mL/min, higher than that of the control group (87.6±5.4) mL/min, all the above differences were statistically significant, P<0.05.Conclusion: Irbesartan in the treatment of hypertensive renal failure patients, can improve the treatment effect, better control of blood pressure, improve renal function, clinical application value is high.
【 Key words 】 Irbesartan;Hypertensive renal failure;Application value
随着高血压疾病发展到终末期阶段,可能会引发多种器官病变导致严重并发症,高血压性肾功能衰竭就是其中之一,严重影响患者的生活质量。对于高血压性肾功能衰竭患者,治疗主要通过药物以控制血压水平,延缓肾损伤,尽可能的保护肾脏功能[1]。本院在高血压性肾功能衰竭患者的治疗中应用厄贝沙坦取得了满意效果,现报道如下。
1资料与方法
1.1基线资料
研究资料来自纳入本院2018年1月至2019年12月期间接收的高血压性肾功能衰竭患者。共86例患者在电脑随机方法下均分为对照组及研究组,各43例患者。其中对照组男30例、女13例,年龄56~78岁、平均(65.2±3.6)岁。……
