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玉屏风颗粒联合阿奇霉素对支原体肺炎患儿心肌酶谱、CRP、血清免疫球蛋白的影响

2020-08-09孙爱英

中外医疗 2020年14期
关键词:阿奇霉素

孙爱英

[摘要] 目的 分析玉屏風颗粒联合阿奇霉素对支原体肺炎患儿的心肌酶谱、CRP与血清免疫球蛋白方面的影响。方法 研究对象方便选择该院2017年1月—2018年12月期间内所收治的140例支原体肺炎患儿,并且按照数字随机表法将其划分为观察组和对照组,每组70例。对照组单纯采用阿奇霉素进行治疗,观察组在阿奇霉素的基础上加用玉屏风颗粒,然后在治疗周期结束后分析两组患儿的临床治疗有效率、血清免疫球蛋白、CRP与心肌酶谱水平,对结果进行统计学分析。结果 在治疗有效率方面,观察组的治疗有效率达到了95.7%,而对照组的治疗有效率只有80.0%,差异有统计学意义(t=3.378,P<0.05);观察组IgG(11.6±2.1) g/L、CRP(7.0±1.4)mg/L、PCT(0.26±0.04)g/L明显优于对照组(9.2±1.8) g/L、(8.6±1.2) mg/L、(0.37±0.04)g/L,差异有统计学意义(t=3.304、3.232、3.148,P<0.05);观察组心肌酶谱水平LDH(133.3±11.4)U/L、CK(95.4±11.0)U/L、CK-MB(19.4±3.3)U/L优于对照组(167.4±12.2)U/L、(111.8±14.1)U/L、(24.1±2.9 )U/L,差异有统计学意义(t=5.445、5.501、5.318,P<0.05),证实了药物联用比单独使用阿奇霉素起到了更显著的作用。结论 玉屏风颗粒联合阿奇霉素可以有效地干山支原体肺炎患儿的各项指标,改善机体的免疫能力,同时保障治疗效果以促进病情的恢复,具有显著的临床应用价值。

[关键词] 玉屏风颗粒;阿奇霉素;支原体肺炎;心肌酶谱;CRP;血清免疫球蛋白

[Abstract] Objective To analyze the effects of Yupingfeng granules combined with azithromycin on myocardial enzymes, CRP and serum immunoglobulin in children with mycoplasma pneumonia. Methods The study subjects convenient selected 140 children with mycoplasma pneumonia treated in the hospital from January 2017 to December 2018, and were divided into observation group and control group according to the digital random table method, with 70 cases in each group. The control group was treated with azithromycin alone, and the observation group was added with Yupingfeng granules on the basis of azithromycin, and then the clinical treatment effectiveness, serum immunoglobulin, CRP and myocardial enzyme levels of the two groups were analyzed after the end of the treatment cycle, statistical analysis of the results. Results In terms of treatment effectiveness, the treatment effectiveness of the observation group reached 95.7%,while the treatment effectiveness of the control group was only 80.0%, the difference was statistically significant(t=3.378, P<0.05); the observation group IgG (11.6±2.1) g/L, CRP (7.0±1.4) mg/L, PCT (0.26±0.04) g/L, significantly better than the control group( 9.2±1.8) g/L, (8.6±1.2)mg/L,(0.37±0.04)g/L. The difference was statistically significant(t=3.304, 3.232, 3.148, P<0.05); the myocardial enzyme level LDH (133.3±11.4) U/L, CK (95.4±11.0) U/L, CK-MB (19.4±3.3) U/L were better than the control group (167.4±12.2)U/L, (111.8±14.1)U/L,(24.1±2.9)U/L, the difference was statistically significant(t=5.445, 5.501, 5.318, P<0.05). The combination of drugs played a more significant role than azithromycin alone. Conclusion Yupingfeng granules combined with azithromycin can effectively improve the indicators of children with Mycoplasma pneumoniae pneumonia, improve the body's immunity, and at the same time guarantee the treatment effect to promote the recovery of the disease, which has significant clinical application value.

[Key words] Yupingfeng granules; Azithromycin; Mycoplasma pneumonia; Myocardial enzymes; CRP; Serum immunoglobulin

小儿支原体肺炎为原发性非典型肺炎,是因为支原体感染所导致,并且是儿童社区获得性肺炎类型中的主要组成部分,通常肺部病变呈现出融合性支气管肺炎,肺泡有炎症渗出物,通常的临床症状为顽固性剧烈咳嗽,部分患儿还可能引起中耳炎、扁桃体炎、肺不张、胸腔积液、心肌炎、脑炎等并发症,一般在通过影像学检查和病原学检查后可以进行确诊。目前的主要治疗措施是通过抗生素抗菌治疗加用其它疗法辅助,而该次研究方便选择该院2017年1月—2018年12月期间内所收治的140例支原体肺炎患儿,所采用的阿奇霉素与玉屏风可以也是西药与调节免疫类中成药的合作治疗,目的在于控制支原体肺炎的发病机制。……

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