咪达唑仑在高龄患者机械通气初期的应用效果及护理
2018-12-07白雪莲
白雪莲
[摘要] 目的 研究與分析咪达唑仑在高龄患者机械通气初期的应用效果及护理方法。方法 方便选取该院2017年1月—2018年3月收治的行机械通气高龄患者100例为对象进行研究,利用计算机随机法将其随机分为对照组和观察组,各50例。机械通气初期对照组未给予任何药物,而观察组给予咪达唑仑。比较分析两组动脉血气、血压、心率、呼吸频率等水平以及不良反应。 结果 观察组氧分压(42.34±6.62)mmHg、二氧化碳分压(41.87±9.08)mmHg、心率(118.13±25.19)次/min、呼吸频率(23.86±4.56)次/min等水平与对照组(52.48±5.32)mmHg、(50.43±15.36)mmHg、(145.32±29.14)次/min、(34.53±5.21)次/min相比均显著较低,差异有统计学意义(t=6.961 9、2.797 3、4.116 0、8.985 9,P=000);而两组舒张压、收缩压等水平对比差异无统计学意义(P>0.05)。结论 高龄患者机械通气初期应用咪达唑仑,可有效提升其气管插管耐受性,并最大限度降低患者氧耗,而通气治疗期间对患者加强针对性护理干预,可有效避免各种不良情绪,因此值得推广应用。
[关键词] 高龄患者;机械通气;初期;咪达唑仑;应用效果;护理
[中图分类号] R472 [文献标识码] A [文章编号] 1674-0742(2018)08(b)-0135-03
Application Effect and Nursing of Midazolam in the Early Stage of Mechanical Ventilation in Elderly Patients
BAI Xue-lian
Department of Respiratory Medicine, 731 Hospital of China Aerospace Science and Industry Corporation, Beijing, 100074 China
[Abstract] Objective To study and analyze the application effect and nursing methods of midazolam in the early stage of mechanical ventilation in elderly patients. Methods A total of 100 elderly patients undergoing mechanical ventilation from January 2017 to March 2018 in the hospital were convenient selected for study and randomly divided into control group and observation group by computer randomization method, 50 cases each. At the initial stage of mechanical ventilation, no drug was administered to the control group, while the observation group was given midazolam. The levels of arterial blood gas, blood pressure, heart rate, respiratory rate, and adverse reactions were compared between the two groups. Results The oxygen partial pressure (42.34±6.62) mmHg, partial pressure of carbon dioxide (41.87±9.08)mmHg, heart rate (118.13±25.19)times/min, respiratory rate (23.86±4.56)times/min and the control group were observed in the observation group(52.48±5.32)mmHg, (50.43±15.36) mmHg, (145.32±29.14)times/min, (34.53±5.21)times/min, all significantly lower, the difference was statistically significant(t=6.961 9、2.797 3、4.116 0、8.985 9,P=0.000); but there was no significant difference in diastolic blood pressure and systolic blood pressure between the two groups(P>0.05). Conclusion The application of midazolam in the early stage of mechanical ventilation can effectively improve the tolerance of endotracheal intubation and minimize the oxygen consumption of the patients. During the ventilation therapy, the patients can strengthen the targeted nursing intervention and can effectively avoid various adverse emotions. Therefore, it is worth promoting.
[Key words] Senior patients; Mechanical ventilation; Early stage; Midazolam; Application effect; Nursing
在现代医学中,机械通气的作用非常显著,而多数患者采取机械通气时,其需接镇痛、镇静,这样既可提升患者机械通气安全感、气管插管舒适度,又能减轻其紧张、焦虑等心理[1-3]。而作为一种水溶性镇静药物,咪达唑仑是苯二氮卓类中枢神经抑制剂,其具有半衰期短、起效快、给药方便、不良反应少等特点,且具有较好的抗惊厥、肌肉松弛、抗焦虑、催眠、镇静等作用,广泛应用于危重患者以及成年人中[4-6]。因此该文即对方便选取该院2017年1月—2018年3月收治的行机械通气高龄患者50例,即对咪达唑仑在高龄患者机械通气初期的应用效果及护理进行了研究,现报道如下。……p>
