张建功 史讯

[摘要] 目的 探讨分析PET/CT联合HRCT在诊断孤立性肺结节中的应用价值，以期为临床诊断提供必要支持。方法 随机抽选该院2016年8月—2018年4月间诊治的78例孤立性肺结节患者作为研究对象，回顾性分析临床资料，分别采用PET/CT、HRCT单项检测及PET/CT联合HRCT进行检测，以病理诊断结果为参考标准，对比3种检测方法的准确性、灵敏度及特异性情况。结果 78例患者病情均由临床病理诊断确诊，其中66例为恶性病灶； PET/CT联合HRCT检测准确性、灵敏度及特异性分别为97.4%、98.0%、96.4%，明显高于PET/CT、HRCT单独检测（χ21=5.778、4.546，P1=0.016、0.040；χ22=4.792、4.271，P2=0.028、0.047）。结论 采用PET/CT联合HRCT检测孤立性肺结节，可显著提高诊断正确率，该检测方案定位精确，具有较高的灵敏度以及特异性，有力支持临床早期诊断，具有重要的临床应用价值。

[关键词] 孤立性肺结节；PET/CT；HRCT；诊断价值

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2018）08（b）-0185-03

The Value of PET/CT Combined with HRCT in the Diagnosis of Solitary Pulmonary Nodules

ZHANG Jian-gong， SHI Xun

PET/CT Room， Yancheng First People's Hospital， Yancheng， Jiangsu Province， 224001 China

[Abstract] Objective To investigate the value of PET/CT combined with HRCT in the diagnosis of solitary pulmonary nodules in order to provide necessary support for clinical diagnosis. Methods A total of 78 patients with solitary pulmonary nodules who were diagnosed and treated in the hospital from August 2016 to April 2018 were selected randomly. The clinical data were analyzed retrospectively. PET/CT， HRCT single test and PET/CT combined with HRCT were used， the results of pathological diagnosis were used as reference standards to compare the accuracy， sensitivity and specificity of the three methods. Results All the 78 patients were diagnosed by clinicopathological diagnosis， of which 66 were malignant lesions. The accuracy， sensitivity and specificity of PET/CT combined with HRCT were 97.4%， 98.0%， and 96.4%， respectively， which were significantly higher than that of PET/CT. HRCT alone detected （χ21=5.778， 4.546， P1=0.016， 0.040； χ22=4.792， 4.271， P2=0.028， 0.047）. Conclusion The use of PET/CT combined with HRCT to detect solitary pulmonary nodules can significantly improve the diagnostic accuracy. The detection scheme has precise positioning， high sensitivity and specificity， and can effectively support early clinical diagnosis. It has important clinical application value.

[Key words] Solitary pulmonary nodules； PET/CT； HRCT； Diagnostic value

肺癌是臨床常见的一种恶性肿瘤，早期明确诊断并及时干预是改善患者预后的重要前提。PET/CT是现阶段应用较多的一项分子影像技术，可用于评估人体病理性改变，在临床疾病诊断方面得到了较为广泛的应用[1]。该院于2016年6月引进了PET/CT并投入了临床使用，该研究随机选取该院2016年8月—2018年4月间诊治的78例孤立性肺结节患者作为研究对象，旨在探讨分析PET/CT联合HRCT在诊断孤立性肺结节中的应用价值，现报道如下。

1 资料与方法

1.1 一般资料

随机抽选该院诊治的78例孤立性肺结节患者，其中男40例，女38例；年龄50～78岁，平均年龄（61.5±3.3）岁；入组对象均无典型临床表现，主要以咳嗽咯痰为主，经临床行胸部CT或常规X线检查确诊病情。……