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缩宫素鼻喷剂在产后止血和催乳中的疗效观察

2016-05-04宜都市第一人民医院超声科湖北宜昌443300

中国医院用药评价与分析 2016年3期
关键词:临床疗效

乐 琴(宜都市第一人民医院超声科,湖北 宜昌 443300)



缩宫素鼻喷剂在产后止血和催乳中的疗效观察

乐琴*(宜都市第一人民医院超声科,湖北 宜昌443300)

DOI10.14009/j.issn.1672-2124.2016.03.022

摘要目的:探讨缩宫素鼻喷剂在产妇产后止血和催乳中的效果。方法:选取宜都市第一人民医院自然分娩或剖宫产的产妇98例作为研究对象,按随机数字表法分为观察组和对照组。对照组48例产妇前3 d鼓励婴儿吸吮,1日6次;观察组50例产妇在对照组处理措施的基础上给予缩宫素鼻喷剂喷鼻,观察2组产妇24 h出血量及奶汁分泌情况。结果:观察组产妇产后24 h出血量为(184.90±20.60) ml,对照组为(278.90±24.80)ml,2组的差异有统计学意义(P<0.05);观察组产妇产后奶汁充足39例(78.00%),奶汁不足9例(18.00%),无奶汁2例(4.00%),对照组产妇产后奶汁充足28例(58.33%),奶汁不足15例(31.25%),无奶汁5例(10.42%),2组的差异有统计学意义(P<0.05)。结论:缩宫素鼻喷剂可以显著减少产妇产后出血量,促进产妇泌乳量的增加,为有效的止血和催乳药物,值得临床推广。

关键词缩宫素鼻喷剂; 产后出血; 催乳; 临床疗效

Observation on Efficacy of Oxytocin Nasal Spray in Treatment of Postpartum Hemorrhage and Prolactin

LE Qin(Dept.of Ultrasound, Yidu Municipal the First People’s Hospital, Hubei Yichang 443300, China)

ABSTRACTOBJECTIVE:To probe into the clinical effects of oxytocin nasal spray in treatment of postpartum hemorrhage and prolactin. METHODS: 98 cases with spontaneous labor or cesarean section admitted into Yidu Municipal the First People’s Hospital were selected to be divided into observation group and control group via the random number table. As for the 48 cases in control, the baby sucking was encouraged before 3 days, 6 times/d; while the 50 cases in observation group were given the oxytocin nasal spray on the basis of the control group. The amount of postpartum hemorrhage and milk in two group of patients were compared. RRESULTS: The 24h postpartum hemorrhage in observation group was (184.90±20.60)ml while in control group was (278.90±24.80) ml, the difference was statistically significant(P<0.05). In observation group, there were 39 cases of postpartum milk sufficient(78.00%), 9 cases of insufficient milk (18.00%), and 2 cases of no milk (4.00%); while in control group were respectively 28 cases (58.33%), 15 cases (31.25%) and 5 cases (10.42%), with statistically significant difference (P<0.05). CONCLUSIONS: Oxytocin nasal spray can effectively reduce the amount of postpartum hemorrhage, promote the lactation yield. It is an effective hemostasis and prolactin drug and worthy of clinical promotion and application.

KEYWORDS Oxytocin nasal spray; Postpartum hemorrhage; Prolactin; Clinical effect

产后出血是产妇产后常见并发症之一[1],产妇在分娩后24 h内阴道出血量超过500 ml则视为产后大出血[2]。产妇在短时间内流血量过大会导致休克或凝血功能障碍等,产后出血是导致产妇临床死亡的主要原因,其发生率已经占到了总分娩人数的2~3%[3]。对于产后出血的患者,抢救不及时会直接影响到患者的生育功能,甚至出现休克或危及生命。目前,产妇产后出血患者治疗药物主要包括卡前列栓、麦角新碱、缩宫素等[4]。本研究探讨宜都市第一人民医院(以下简称“我院”)给予常规药物加缩宫素治疗在减少产后出血中的疗效及对催乳的影响,现报告如下。

1资料与方法

1.1资料来源

选择我院2014年6月—2015年6月自然分娩或剖宫产妇98例作为研究对象,所有患者均未发现相关并发症或合……

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