王　荣(十堰市郧阳区中医医院风湿科，湖北 十堰　442599)



玻璃酸钠膝关节腔内注射治疗骨关节病的疗效观察

王荣*(十堰市郧阳区中医医院风湿科，湖北 十堰442599)

DOI10.14009/j.issn.1672-2124.2016.03.019

摘要目的：探讨应用玻璃酸钠治疗类风湿性关节炎的疗效及治疗中的护理方法。方法：选择湖北省十堰市郧阳区中医医院从2013年2月—2015年3月的类风湿性关节炎患者120例作为研究对象，按随机数字表法分为对照组和观察组，每组各60例。对照组患者给予常规综合治疗和护理，即给予口服美洛昔康片，超短波以及关节功能锻炼；观察组患者在对照组患者的综合治疗和护理的基础上给予玻璃酸钠注射治疗和护理措施，比较2组患者的恢复情况。结果：经过5周的治疗，2组患者的治疗效果明显存在差异，观察组患者治疗后总有效率达到了91.67%(55/60)；明显高于对照组患者总有效率80.00%(48/60)，差异有统计学意义(P<0.05)；从关节炎程度的评分来看，治疗后观察组患者0分患者增加7例，11分以上患者减少6例，对照组患者0分患者只增加1例，11分以上患者只减少3例，观察组患者的治疗可控制效果明显优于对照组，差异有统计学意义(P<0.05)。结论：玻璃酸钠注射治疗类风湿性关节炎疗效较好，值得推广。

关键词类风湿； 关节炎； 玻璃酸钠； 疗效； 护理方法

Observation on Efficacy of Sodium Hyaluronate in Intra-articular Injection Treatment of Osteoarthrosis

WANG Rong(Dept.of Rheumatology，Hubei Shiyan Xunyang District Traditional Chinese Medicine Hospital，Hubei Shiyan 442599，China)

ABSTRACTOBJECTIVE：To investigate the efficacy of sodium hyaluronate in treatment of rheumatoid arthritis，and the nursing method in the treatment.METHODS:120 cases of patients with rheumatoid arthritis admitted into Hubei Shiyan Xunyang District Traditional Chinese Medicine Hospital from Feb. 2013 to Mar.2015 were collected to be divided into control group and observation group via the random number table，with 60 cases in each.The control group were given conventional treatment and care，namely，oral Meloxicam tablets，ultrashort wave and joint function exercise. The observation group additionally received give sodium hyaluronate injection treatment and nursing measures based on the control group. By contrast，the recovery of two groups were compared.RESULTS:After treatment of five weeks，the curative effects of two group of patients showed obvious differences.The total effective rate of observation group was 91.67%(55/60)，significantly higher than that of control group 80.00%(48/60)， with statistically significant difference(P<0.05).As for the extent of osteoarthrosis score in observation group，patients of zero increased 7 cases，patients of more than 11 points decreased 6 cases； while in control group，patients of zero increased 1 case，patients of more than 11 points decreased 3 cases. The control effects of observation group was significantly better than that of control group， with statistically significant difference(P<0.05). CONCLUSIONS: The efficacy of sodium hyaluronate in intra-articular injection treatment of osteoarthrosis in clinic is significant.It is worthy of clinical promotion and application.

KEYWORDSRheumatoid； Arthritis； Sodium hyaluronate； Efficacy； Nursing methods

类风湿性关节炎在临床上的发生率越来越高，发病年龄逐渐降低，所以找到能够有效治疗疾病的方法尤为重要。本病是一种以累及周围关节为主的多系统性炎症性的自身免疫性疾病，女性属于多发性人群，其主要临床表现为关节疼痛、肿胀，关节活动功能下降等，严重者会导致关节机体萎缩以及关节功能消失等[1]，其发病多与自身的免疫机制有关。本研究就玻璃酸钠注射治疗类风湿性关节炎的疗效和护理措施进行了对比分析，现报告如下。

1资料与方法