陈丽珍+林莉萍

[摘要] 目的 探讨新辅助化疗治疗宫颈癌的临床疗效。 方法 选取我院120例诊断为宫颈癌的患者分为治疗组60例患者均采用新辅助化疗治疗，对照组60例患者采用传统治疗方式治疗。 结果 治疗组60例患者在接受新辅助化疗方法治疗后2周进行妇科检查后，发现患者肿瘤直径较前缩小，占总数的75.00%，对照组60例患者采用手术治疗患者59例，其中40例患者手术成功。 结论 宫颈癌患者术前进行新辅助化疗方式化疗可使得患者肿瘤缩小，降低了淋巴结的转移率，同时可以提高患者的手术切除率，是一种新时代的治疗宫颈癌的有效方式。

[关键词] 新辅助化疗；宫颈癌；淋巴结转移；肿瘤直径

[中图分类号] R737.8 [文献标识码] B [文章编号] 1673-9701（2015）25-0038-03

Clinical efficacy analysis of neoadjuvant chemotherapy in treatment of 60 patients with cervical cancer

CHEN Lizhen LIN Liping

Department of Gynecology and Obstetrics， Jingdezhen First People's Hospital in Jiangxi Province， Jingdezhen 333000，China

[Abstract] Objective To explore and analyze the clinical effects of neoadjuvant chemotherapy for the treatment of cervical cancer. Methods A total of 120 patients diagnosed with cervical cancer of our hospital were selected， of which 60 patients were assigned to the treatment group and given neoadjuvant chemotherapy treatment and 60 patients were assigned to the control group and given traditional treatment. Results In the treatment group， 2 weeks after the neoadjuvant chemotherapy treatment， gynecological examination was conducted and showed that the diameter of tumor reduced compared to before， accounting for 75.00% of the total. In the control group， 59 out of the 60 patients were given surgical treatment， of which 40 patients achieved surgical success. Conclusion Preoperative implementation of neoadjuvant chemotherapy can reduce tumor size of the patients with cervical cancer， reduce the lymph node metastasis rate and improve the patients surgical excision rate， which is an effective modern method to treat cervical cancer.

[Key words] Neoadjuvant chemotherapy； Cervical cancer； Lymph node metastasis； Tumor diameter

目前宫颈癌是全世界危害妇女最为常见的妇科恶性肿瘤之一[1]，其发病率在妇女的恶性肿瘤中高居第二名[2]，而且宫颈癌是女性生殖器宫恶性肿瘤的第一名，在世界范围内统计中每年大约有50万左右的宫颈癌新发病，其发病率占所有癌症的新发病率有5%，在发展中国家中宫颈癌的发病率在全世界占80%[3，4]。既往人们认为宫颈癌是一种对于化疗并不敏感的肿瘤，但是近年来的研究发现新辅助化疗对于治疗宫颈癌较为铭感，尤其是新辅助化疗对于宫颈鳞癌更为敏感，新辅助化疗是在手术前或放疗前给予全身化疗，同时也称早期化疗，对于肿瘤直径超过4 cm的Ⅰb2～Ⅱa期患者给予术前行新辅助化疗对于手术治疗效果更加显著，报道如下。……