姜成宇 黄云彤 邢志勇 雷雪 陈祥凤 徐启江

摘  要：蛋白质与酶工程作为高等院校生物技术和生物工程专业人才培养的核心课程之一，立足拓展学生的思维能力、实际问题的解决能力和全球变革下的综合视野。通过在蛋白质与酶工程课程教学的过程中引入OBE教育理念，对教学模式、课程体系、评价机制、课程思政等方面进行改革，从而提高教学质量、活化学生创新实践能力、满足社会企业的岗位需求，落实“立德树人”教育目标。期末“自我能力评价”问卷调查结果显示，学生对该门课程的混合式教学模式认同率超过80%，对自身能力提升评价在80分以上的学生超过50%。因此，基于OBE理念的蛋白质与酶工程课程教学改革在培养学生开拓创新方面具有积极的促进作用，为适应新时代复合应用型人才培养体系的课程教学改革提供必要的参考。

关键词：蛋白质与酶工程；OBE理论；课程改革；新教学模式；课程体系

中图分类号：G642         文献标志码：A          文章编号：2096-000X（2023）21-0115-05

Abstract： As one of the core courses for the cultivation of biotechnology and bioengineering majors in universities， Protein and Enzyme Engineering aims to expand students' thinking ability， practical problem-solving ability， and comprehensive vision under global change. By introducing the OBE education concept into the teaching process of protein and enzyme engineering， the teaching model， curriculum system， evaluation mechanism， curriculum ideology politics， and other aspects are reformed， so as to improve the teaching quality， activate students' innovation and practice ability， meet the post needs of social enterprises， and implement the education goal of "cultivating virtues and cultivating people". The results of the "self-ability evaluation" questionnaire at the end of the term show that more than 80% of the students agree with the blended teaching mode of this course， and more than 50% of the students give more than 80 points for their own ability improvement. Therefore， the protein and enzyme engineering curriculum teaching reform based on the concept of OBE plays a positive role in cultivating students' innovation and provides a necessary reference for the curriculum teaching reform to adapt to the composite applied talent training system in the new era.

Keywords： Protein and enzyme engineering; OBE theory; Curriculum reform; New teaching model; Curriculum system

在1981年，美国教育学者William G. Spady首次提出了成果导向教育（Outcomes-Based Education，OBE）的概念，是以质量保证和持续改进为基本指导思想和出发点，强调以学生为主体，以目标成果为导向，重视学生的学习结果的教育理念[1]。该理念以学生产出结果为驱动，而非传统上内容驱动和单向知识传输教育，因此，OBE教育模式被认为是一种教育范式的革新。自数年间的实践摸索下，OBE教育理念业已成为满足我国应用型人才培养的理性认识，教育教学改革主旨思想的主观要求[2-3]。……