刘哲 陈葳

摘要：目的：观察血流感染临床诊断中实行血培养、降钙素原定量检测的价值。方法：观察对象为就医于我院的血流感染患者80例，均实行血培养、降钙素原定量检测，对诊断结果进行分析。结果：对比血培养阴性结果者，阳性结果者降钙素原水平明显提升，P<0.05;相比感染革兰阳性杆菌者，感染革兰阴性杆菌者降钙素原水平明显提升，P<0.05;降钙素原呈现较高的阴性预测力。结论：血流感染临床诊断中实行血培养、降钙素原定量检测联合诊断效果更佳，建议推广。

关键词：血流感染;血培养;降钙素原;诊断;定量检测

Objective： To observe the value of blood culture and calcitonin quantitative detection in the clinical diagnosis of blood flow infection. Methods： 80 patients with blood flow infection were observed， and blood culture and calcitonin were measured quantitatively， and the diagnosis results were analyzed. Results： the level of procalcitonin was significantly increased in the negative results of blood culture， P < 0.05; Compared with those infected with Gram-positive bacteria， the level of procalcitonin in Gram-negative bacilli was significantly increased， P < 0.05; Calcitonin had a higher negative predictive power. Conclusion： the combination of blood culture and calcitonin quantitative detection is better in the clinical diagnosis of blood flow infection， and it is suggested to be popularized.

Key words： blood flow infection; Blood culture; Calcitonin; diagnosis; Quantitative detection

在临床上血流感染作为一种感染性严重疾病，致病原因为血流中侵入毒素、真菌、细菌所致[1]。需尽早实行诊断。而血培养、降钙素原定量检测为2种常用诊断方法，本次研究对其应用价值进行观察，结果如下。

1資料与方法

1.1一般资料

观察对象为就医于我院的血流感染患者80例（2020.3-2021.3），（51.35±6.15）岁为年龄均值（21-76岁），48例、32例为男女患者数。依据血培养结果，46例阴性结果，34例阳性结果。

1.2方法

血培养检测方法，消毒静脉抽血部位，对血液进行抽取，样本量为10ml，在无菌环境下，在厌氧培养瓶（血液制品）中注入样本。1例患者对1套血培养进行送检，即厌氧血培养瓶、需氧血培养瓶，检测血培养结果，利用全自动微生物系统鉴定病原菌。

降钙素原定量检测：对静脉血进行抽取，样本量为5ml，在真空采血管中注入，待血液呈现凝固状态后，以每分钟3500r转速进行5min离心处理，对血清进行分离，利用全自动荧光定量分析仪实行检测，0-0.05ng/ml为正常参考值。……