李旭 王晓军 徐晓文 袁建军

[摘要] 目的 探討行单孔胸腔镜下肺叶切除术患者应用双曲型管引流的有效性、安全性。 方法 选取2019年1月至2020年3月在我院进行单孔胸腔镜下肺叶切除术的肺癌患者158例，按照随机数字表法分为对照组和双曲管组，每组各79例，对照组术后给予患者留置传统引流管进行引流，双曲管组术后给予患者双曲型管引流。对比两组患者炎症因子指标[白介素-6（Interleukin-6，IL-6）、白介素-10（Interleukin-10，IL-10）、C-反应蛋白（C-reactive protein，CRP）];对比两组患者术后并发症、视觉模拟评分法（Visual simulation scoring，VAS）评分、抑郁自评量表（Self rating depression scale，SDS）评分、生活质量量表（Quality of life scale，SF-36）。 结果 两组患者手术时间、淋巴结清扫数量相比，差异无统计学意义（P>0.05）;与对照组相比，双曲管组胸腔引流量较少，差异有统计学意义（P<0.05）;与对照组相比，双曲管组IL-6、IL-10、CRP水平较低，差异有统计学意义（P<0.05）;与对照组相比，双曲管组患者生理、心理、躯体、活力评分有所上升（P<0.05）;与对照组相比，双曲管组患者VAS、SDS评分较低（P<0.05）;与对照组相比，双曲管组术后并发症总发生率较低（P<0.05）。 结论 使用双曲型管对行单孔胸腔镜下肺叶切除术患者进行引流，能够改善患者的临床症状，降低炎症因子水平，减少并发症的发生，有着较好的安全性。

[关键词] 单孔胸腔镜;肺叶切除术;双曲型管引流;生活质量

[中图分类号] R734.1          [文献标识码] B          [文章编号] 1673-9701（2021）32-0067-04

[Abstract] Objective To explore the efficacy and safety of hyperbolic tube drainage in patients undergoing single-hole thoracoscopic lobectomy. Methods A total of 158 patients with lung cancer who received single-hole thoracoscopic lobectomy in our hospital from January 2019 to March 2020 were selected and divided into the control group（n=79） and the hyperbolic tube group（n=79） according to a random number method. The patients in the control group were given an indwelling traditional drainage tube for drainage after the operation， while the patients in the hyperbolic tube group were given hyperbolic tube drainage after the operation. Inflammatory factor indicators [interleukin-6（IL-6），interleukin-10 （IL-10），C-reactive protein （CRP）] were compared between the two groups. The postoperative complications， visual analog scale （VAS），self-rating depression scale （SDS） score，and quality of life scale （SF-36） scale were compared between the two groups. Results The differences in the operation time and the number of dissected lymph nodes between the two groups were not statistically significant（P>0.05）.Compared with the control group， the thoracic drainage volume in the hyperbolic tube group was less， and the difference was statistically significant（P<0.05）. The IL-6，IL-10 and CRP levels in the hyperbolic tube group were lower， and the difference was statistically significant（P<0.05）. The physical， psychological， physical， and vitality scores in the hyperbolic tube group were increased（P<0.05）; the VAS and SDS scores in the hyperbolic tube group were lower（P<0.05）. Compared with the control group， the total incidence rate of postoperative complications in the hyperbolic tube group was lower（P<0.05）. Conclusion The use of hyperbolic tubes for drainage in patients undergoing single-hole thoracoscopic lobectomy can improve the clinical symptoms of patients， reduce the level of inflammatory factors， reduce the occurrence of complications， with reasonable safety.

[Key words] Single-hole thoracoscopic surgery; Lobectomy; Hyperbolic tube drainage; Quality of life

原发性支气管肺癌可简称为“肺癌”，起源于气管、支气管黏膜或腺体，是一种最常见的肺部原发性恶性肿瘤[1-2]。随着社会的进步和医疗设备、技术的不断发展，单孔胸腔镜下肺叶切除术已然发展成为临床治疗肺癌的常用治疗手段。……