郑丹 王英瑞

【摘要】目的探究心理干預对甲状腺功能减退抑郁患者负性情绪的影响。方法选取2014年1月～2016年12月间收治的86例甲状腺功能减退抑郁患者为受试对象，按照随机数字表分为观察组与对照组各43例。对照组予以常规护理干预，观察组在对照组基础上实施心理干预。比较干预前及干预1个月后，两组患者抑郁程度[Hamilton抑郁评分量表17项（HAMD17）]、焦虑程度[Hamilton焦虑评分量表（HAMA）]、甲状腺功能[血清促甲状腺激素（TSH）、血清总甲状腺激素（TT4）水平]变化。结果干预1个月后，两组患者HAMD、HAMA评分均较干预前显著下降（P均<0.05），观察组患者HAMD、HAMA评分下降更明显（P均<0.01）。干预1个月后，两组患者TSH水平均较干预前显著下降（P均<0.05），观察组患者TSH水平下降更明显（P<0.01）。两组患者TT4水平均较干预前显著提升（P<0.05），观察组患者TT4水平提升更明显（P<0.01）。结论心理干预能有效改善甲状腺功能减退抑郁患者负性情绪，对提升其治疗效果有利。

【关键词】心理干预；甲状腺功能减退；抑郁；负性情绪

中图分类号：R581.2 文献标识码：ADOI：10.3969/j.issn.10031383.2018.02.027

Study on effect of psychological intervention on negative emotions

in patients with hypothyroidism and depression

ZHENG Dan，WANG Yingrui

（Xinxiang Central Hospital，Xinxiang 453000，China）

【Abstract】ObjectiveTo explore the effect of psychological intervention on negative emotions in patients with hypothyroidism and depression.Methods86 patients with hypothyroidism and depression treated in our hospital from January 2014 to December 2016 were selected for the study and were divided into observation group （n=43） and control group （n=43） according to random number table method.The control group were given routine nursing intervention，and based on which the observation group were given psychological intervention.And then，depression degree [Hamilton Depression Rating Scale17 （HAMD17）]，anxiety degree [Hamilton Anxiety Rating Scale （HAMA）]，thyroid function [serum thyroid stimulating hormone （TSH） and total serum thyroid hormone （TT4）] were compared between the two groups before intervention and after 1 month of intervention.ResultsAfter 1 month of intervention，the HAMD scores and HAMA scores in the two groups were significantly lower than those before intervention（P<0.05），and those in the observation group were significantly lower than those in the control group（all P<0.01）.The TSH levels in both groups were significantly lower than those before intervention （P<0.05），and that in the observation group decreased more significantly than that in the control group（P<0.01）.The TT4 levels in the two groups all significantly higher than those before intervention（all P<0.05），and that in the observation group was significantly higher than that in the control group（all P<0.01）.ConclusionPsychological intervention can effectively improve the negative emotions of patients with hypothyroidism and depression，and it is beneficial to improve the treatment effects.

【Key words】psychological intervention；hypothyroidism；depression；negative emotions

甲状腺功能减退是临床常见的内分泌疾病，多由甲状腺激素分泌或生物活性不足所引起。患者常表现出全身性的代谢抑制，不仅累及运动、消化、心血管等系统功能，还可明显干扰到精神状况。多数患者患病后表现出记忆力减退、反应迟钝、表情淡漠、多虑等症状，给日常生活及工作带来极大不便，随着生活负性事件愈发频现，极易产生心理压力及负性情绪。笔者通过心理干预改善甲状腺功能减退患者负性情绪，取得一定效果，现报道如下。

1资料与方法1.1一般资料 选取2014年1月～2016年12月间我院收治的86例甲状腺功能减退抑郁患者为受试对象，按照随机数字表分为观察组与对照组各43例。观察组男28例，女15例，平均年龄（43.2±125）岁，平均病程（4.6±2.4）年，原发性甲状腺功能减退16例，继发性甲状腺功能减退27例，文化程度：初中及以下8例，高中或中专17例，大专及以上18例；……