乐军

[摘要] 目的 分析補肾活血汤配合鲑鱼降钙素治疗老年骨质疏松性腰椎骨折的临床效果。 方法 选择2015年5月～2017年6月来我院就诊的老年骨质疏松性腰椎骨折患者109例为研究对象，采用随机数字表法分为对照组和观察组，109例患者在接受PKP治疗的基础上，对照组采用皮下注射鲑鱼降钙素，观察组在对照组基础上联合补肾活血汤，比较两组临床效果。 结果 对照组治疗前ODI（46.83±3.91）与观察组治疗前ODI（45.98±4.03）比较差异不显著（P>0.05），经治疗后对照组ODI（38.91±4.09）与观察组ODI（26.28±5.21）差异显著（P<0.05）。重复测量方差分析发现，两组在组间和时间具有统计学差异（P<0.05），但组别与时间的交互作用差异无统计学意义（P>0.05），两组术前BMD（0.69±0.06）、术后1个月（0.72±0.09）与观察组术前BMD（0.69±0.06）、术后1个月（0.72±0.09），差异不显著（P>0.05）。治疗后对照组BMD术后3个月（0.72±0.09）、术后6个月（0.72±0.08）与对照组BMD术后3个月（0.73±0.09）、术后6个月（0.73±0.09），差异显著（P<0.05）。对照组总有效率45例（83.33%）与观察组总有效率53例（96.36%），差异显著（P<0.05）。 结论 补肾活血汤配合鲑鱼降钙素治疗老年骨质疏松性腰椎骨折临床效果显著，值得推广。

[关键词] 补肾活血汤；鲑鱼降钙素；老年；骨质疏松性腰椎骨折

[中图分类号] R683；R580 [文献标识码] B [文章编号] 1673-9701（2018）10-0077-03

Clinical observation of Bushen Huoxue decoction combined with salmon calcitonin in treating senile osteoporotic lumbar fracture

YUE Jun

Department of Orthopedics，Guangzhou Hospital of Traditional Chinese Medicine，Guangzhou 510130，China

[Abstract] Objective To analyze the clinical effect of Bushen Huoxue decoction combined with salmon calcitonin in the treatment of senile osteoporotic lumbar fractures. Methods A total of 109 patients with osteoporotic lumbar vertebral fracture treated in our hospital from May 2015 to June 2017 were selected as the study subjects.The patients were divided into control group and observation group by random number table. 109 patients were all treated with PKP. On the basis of PKP treatment， the control group received salmon calcitonin subcutaneously. The observation group was treated with Bushen Huoxue decoction on the basis of the treatment of the control group. The clinical effects were compared between the two groups. Results There was no significant difference in the ODI of the control group before treatment（46.83±3.91）and that of the observation group before treatment（45.98±4.03）（P>0.05）. After treatment， there was significant difference in the ODI of the control group（38.91±4.09）and that of the observation group （26.28±5.21）（P<0.05）. Repeated measures analysis of variance showed that the two groups had statistical difference between groups and time（P<0.05）. But there was no significant difference in the interaction between groups and time（P>0.05）. There was no significant difference between the preoperative BMD（0.69±0.06） and postoperative 1-month BMD （0.72±0.09） in the control group and the preoperative BMD（0.69±0.06） and postoperative 1-month BMD（0.72±0.09） in the observation group（P>0.05）. After treatment， there was significant difference between the postoperative 3-month BMD（0.72±0.09） and postoperative 6-month BMD（0.72±0.08） in the control group and the postoperative 3-month BMD（0.73±0.09） and postoperative 6-month BMD（0.73±0.09） in the observation group（P>0.05）. There was significant difference in the total effective rate cases of 45（83.33%） in the control group and total effective rate cases of 53（96.36%） in the observation group（P<0.05）. Conclusion Bushen Huoxue decoction combined with salmon calcitonin in the treatment of senile osteoporotic lumbar fracture has significant clinical effect， which is worthy of promotion.

[Key words] Bushen Huoxue decoction； Salmon calcitonin； Senile； Osteoporotic lumbar fractures

骨质疏松症是一种因多种因素导致的骨病[1]，由于骨质疏松患者非常容易出现骨折，骨折也是骨质疏松最严重的并发症。其中老年患者的发病率占多数。其中胸腰椎骨折的发生率在临床上比较常见[2]。在我国中医理论中，认为骨质疏松属于“骨萎”等范畴[3]，人体因肾气热，导致腰脊不举，进而出现骨枯而髓减。中医认为骨质疏松性腰椎骨折与肾气不足有关，肾主骨，骨质疏松诸症多为肾虚引起。本次研究使用中西药结合治疗，其中使用补肾活血汤，整个药方运用于骨质疏松性腰椎骨折患者，能够起到养肝肾、强筋骨、填精髓等功效。本次研究在2015年5月～2017年6月间共纳入109例患者进行临床分析，探究针对老年骨质疏松性腰椎骨折患者采用中西医结合治疗的临床效果，现报道如下。