毕梦　王丛　杨飞

【摘要】 目的：观察聚焦超声结合糠酸莫米松鼻喷雾剂治疗中重度变应性鼻炎（AR）的临床效果。方法：回顾性分析126例于笔者所在医院就诊中重度AR患者的临床资料，按治疗方法分为观察组（66例，行聚焦超声结合糠酸莫米松鼻喷雾剂治疗）和对照组（60例，给予糠酸莫米松鼻喷雾剂治疗），术后随访6个月，记录两组患者鼻塞、喷嚏、清涕、鼻痒等症状视觉模拟量表评分（VAS）变化，评价治疗效果。结果：治疗后6个月，两组患者各症状评分均有所下降，且观察组各症状评分均低于对照组，差异均有统计学意义（P<0.05）；观察组总有效率为92.42%，显著高于对照组的 80.00%，差异有统计学意义（P<0.05）。结论：聚焦超声结合糠酸莫米松鼻喷雾剂治疗AR，能够明显改善患者鼻塞、喷嚏等症状，具有确切的临床疗效，适合用于中重度AR的临床治疗。

【关键词】 聚焦超声； 鼻喷雾； 变应性鼻炎

doi：10.14033/j.cnki.cfmr.2018.4.008 文献标识码 B 文章编号 1674-6805（2018）04-0017-02

Clinical Effect Observation of Focused Ultrasound and Nasal Spray in Treatment of Moderate and Severe Allergic Rhinitis/BI Meng，WANG Cong，YANG Fei.//Chinese and Foreign Medical Research，2018，16（4）：17-18

【Abstract】 Objective：To observe the clinical effcacy of focused ultrasound combined with Mometasone Furoate Nasal Spray in the treatment of moderate and severe allergic rhinitis （AR）.Method：The clinical data of 126 ptients with moderate and severe AR in the authors hospital were analyzed retrospectively，according to the therapeutic method，the patients were divided into observation group （66 cases，treated with focused ultrasound combined with Mometasone Furoate Nasal Spray） and control （60 cases，treated with Mometasone Furoate Nasal Spray）.The patients were followed up for 6 months，the visual analogue scale （VAS） scores of two groups with nasal congestion，sneezing，clear nose and nasal itching were recorded，and the therapeutic effects were evaluated.Result：After 6 months of treatment，the scores of each symptom were decreased in two groups，and the scores in observation group were lower than the control group，the total effective rate of observation group was 92.42%，significantly higher than 80.00% of control group，the differences were statistically significant（P<0.05）.Conclusion：Focused ultrasound combined with Mometasone Furoate Nasal Spray in the treatment of AR can significantly improve patient，s clinical symptoms，and it has definite clinical curative effeect.

【Key words】 Focused ultrasound； Nasal spray； Allergic rhinitis

First-authors address：Deyang Peoples Hospital，Deyang 618000，China

變应性鼻炎（AR）是一种鼻部变态反应性疾病，是由于特应性个体接触花粉、灰尘等过敏原，从而诱导机体发生鼻黏膜炎性反应，导致患病[1]。AR早期鼻痒、喷嚏等症状较轻，患者多数可耐受，从而忽视病情，导致患者病情反复发作，逐渐发展为中重度AR，并引发严重的并发症，从而影响患者的生活质量[2]。目前，对于中重度AR的治疗多采用糖皮质激素类药物，随着超声治疗技术的不断发展，外科治疗不断应用于中重度AR中，并取得了显著的效果[3]。聚焦超声属于超声治疗的前沿技术之一，本研究采用聚焦超声结合糠酸莫米松鼻喷雾剂治疗中重度AR，观察此方法的临床疗效，旨在为中重度AR的临床治疗提供参考。

1 资料与方法

1.1 一般资料

回顾性分析2016年6月-2017年1月就诊于笔者所在医院耳鼻喉外科的126例中重度AR患者的临床资料。……