莫沙必利联合阿嗪米特治疗胆汁反流性胃炎的临床疗效观察
2017-07-12黄嫦
黄嫦

摘要:目的 探究莫沙必利联合阿嗪米特治疗胆汁反流性胃炎的临床疗效。方法 以2014年7月~2015年8月我院确诊的110例胆汁反流性胃炎患者为研究对象,按抽签法分为两组,每组各55例。对照组予以莫沙比利联合碳酸铝镁进行治疗,观察组实施莫沙必利联合阿嗪米特治疗。比较两组患者的疗效及症状改善情况。结果 观察组各症状评分(腹胀、反酸、腹痛、恶心)均优于对照组,差异显著(P<0.05);观察组治疗总有效率为98.18% ,高于对照组的81.82%,差异显著(P<0.05)。结论 莫沙必利联合阿嗪米特治疗胆汁反流性胃炎可帮助患者缓解临床症状,提高患者的生存质量。
关键词:莫沙必利;阿嗪米特;胆汁反流性胃炎;临床疗效
中图分类号:R573.3 文献标识码:A 文章编号:1006-1959(2017)13-0008-02
Abstract:Objective To explore the clinical effect of Mosapride combined with azintamide in the treatment of bile reflux gastritis.Methods 110 cases of bile reflux gastritis patients as the research object in July 2014~August 2015 in our hospital,were randomly divided into two groups,55 cases in each group.The control group was given mosapride combined with aluminum magnesium carbonate for treatment,the observation group received mosapride combined with azintamide treatment.Efficacy and symptoms of the two groups were observed.Results In the observation group,the symptom score(abdominal distension,acid regurgitation,abdominal pain,nausea)were better than the control group,the difference was significant(P<0.05);the total efficiency of the observation group was 98.18%,higher than 81.82% in the control group,the difference was significant(P<0.05).Conclusion Mosapride combined with azintamide on bile reflux gastritis may help patients relieve clinical symptoms,improve the quality of life of patients.
Key words:Mosapride;Azintamide;Bile reflux gastritis;Clinical curative effect
膽汁返流性胃炎也称碱性反流性胃炎,是一种常见的消化系统疾病。其病因在于十二指肠内物质流入胃里后,破坏胃粘膜的正常生理解剖结构,造成胃糜烂或炎症[1]。近年来,其发病率呈上升趋势。该病的特殊性致使其治疗过程存在极大难度,威胁患者的生命安全。因此,如何提高治疗效果,减轻因疾病给患者带来的痛苦显得尤为重要。我院对胆汁反流性胃炎患者实施莫沙必利联合阿嗪米特进行治疗,取得了显著效果,现总结如下。
1资料与方法
1.1一般资料
以2014年7月~2015年8月于我院经胃镜检查确诊为胆汁反流性胃炎,接受药物治疗患者110例为研究对象,按抽签法分为两组,每组各55例。对照组中男31例,女24例;年龄20~75岁,平均年龄(47.8±3.6)岁;病程为1~11年,平均病程(5.18±1.16)年。观察组中男30例,女25例;年龄22~75岁,平均年龄(46.8±3.9)岁;病程为2~13年,平均病程(5.27±1.37)年。患者均存在恶心呕吐、腹胀腹痛、反酸烧心等临床症状。两组患者在性别、年龄、病程等一般资料比较,差异方无统计学意义(P>0.05),存在可比性。……
