糖皮质激素联合抗生素治疗未足月胎膜早破效果探讨
2017-06-19梁燕飞
梁燕飞

【摘要】 目的:探讨糖皮质激素联合抗生素治疗未足月胎膜早破效果。方法:选择笔者所在医院2013年3月-2016年3月收治的200例未足月胎膜早破产妇,通过随机分配的方法,分为对照组和观察组,各100例。对照组产妇采用单纯抗生素治疗的方式,观察组产妇在此基础上,应用糖皮质激素进行治疗,并对两组产妇的妊娠情况进行分析。结果:观察组新生儿窒息、胎儿窘迫及绒毛膜羊膜炎发生率均低于对照组,差异有统计学意义(P<0.05)。结论:糖皮质激素联合抗生素治疗未足月胎膜早破临床效果明显,能够大大提高产妇的妊娠质量,保证母婴安全,值得在临床中推广。
【关键词】 糖皮质激素; 抗生素; 未足月胎膜早破
doi:10.14033/j.cnki.cfmr.2017.13.008 文献标识码 B 文章编号 1674-6805(2017)13-0018-02
【Abstract】 Objective:To investigate the effect of Glucocorticoid in the treatment of preterm premature rupture of membranes with Antibiotics.Method:200 cases of premature rupture of membranes in the authors hospital from March 2013 to March 2016 were divided into two groups:control group and observation group,100 cases in each group.The control group was treated with simple antibiotic treatment,the observation group was based on this,the use of glucocorticoid treatment,and the two groups of maternal pregnancy analysis.Result:In the control group,maternal pregnancy was:13% cases of fetal distress,the incidence rate was 13,13 cases of neonatal asphyxia,the incidence rate was 13%,25 cases of chorionic amniotic membrane,the incidence rate was 25%.In the observation group,the incidence of fetal distress in 5 cases,the incidence rate was 5%,3 cases of neonatal asphyxia,the incidence rate was 3%,and the incidence rate was 1%,the differences were statistically significant(P<0.05).Conclusion:The clinical effect of Glucocorticoid and Antibizotics in the treatment of preterm premature rupture of membranes is obvious,and it can greatly improve the quality of maternal pregnancy,ensure the safety of mother and infant,and is worth popularizing in clinical practice.
【Key words】 Glucocorticoids; Antibiotics; Preterm premature rupture of membranes
First-authors address:Nahai District Ninth Peoples Hospital of Foshan City,Foshan 528203, China
胎膜早破是目前產科常见的并发症,胎膜早产会对母婴造成严重的伤害,未足月胎膜早破主要是由于创伤、感染以及宫颈内口松弛导致的,处理胎膜早破对于改善母婴预后有着重要的作用[1]。近年来,我国胎膜早破的发生率不断上升,为了保证母婴安全,降低感染发生率,改善母婴的预后,笔者所在医院对2015年3月-2016年3月收治的胎膜早破产妇采取糖皮质激素联合抗生素进行治疗,取得了较好的效果,具体报告如下。
1 资料与方法
1.1 一般资料
选择笔者所在医院2015年3月-2016年3月收治的200例未足月胎膜早破产妇,通过随机分配的方式分为对照组与观察组,每组50例。对照组产妇年龄20~39岁,平均(29.24±1.27)岁;观察组产妇年龄21~39岁,平均(29.31±1.30)岁。两组患者一般资料比较差异无统计学意义(P>0.05),具有可比性。
1.2 方法
对照组产妇采用单一抗生素治疗,头孢呋辛钠静脉滴注预防感染,剂量3 g/d,2次/d,产前产后共使用3次抗生素。……
