姜禹存 顾琳 陆赛花 徐峰

摘 要 目的：通过真实世界调查研究公众对于药品价格和国产仿制药的看法，及对用药选择的可能影响，探讨分析相关认知因素，以推动仿制药政策的落地实施。方法：参考相关文献，设计调查问卷，在问卷星应用程序上发布，对数据进行统计学处理。结果：共收集294份有效问卷。问卷有效率为100%。在全部问卷中，89人为非医药行业人员，205人为从事医药或相关行业人员。50.34%的问卷担忧仿制药政策下药品价格过低，药品质量可能得不到保障。多数公众支持国产仿制药，但是在遭遇重大疾病时仍倾向选择原研药。结论：为了消除公众对仿制药质量和疗效的不当认知，加深公众对国产仿制药政策的了解，针对原研药-仿制药一致性评价的合理用药科普教育非常必要。

关键词 药品价格 仿制药 原研药 一致性评价 认同

中图分类号：R181.35 文献标志码：C 文章编号：1006-1533（2021）15-0047-03

Real world survey of the publics recognition on drug prices and domestic generic drugs

JIANG Yucun1，2， GU Lin3， LU Saihua1， XU Feng1

（1. the Sixth Peoples Hospital South Campus affiliated to Shanghai Jiao Tong University， Shanghai 201400， China； 2. School of Pharmacy， Shanghai University of Medicine & Health Sciences， Shanghai 201318， China； 3. Shanghai Qingpu Hospital of Traditional Chinese Medicine， Shanghai 201700， China）

ABSTRACT Objective： To study the publics views on drug prices and domestic generic drugs and their possible influence on drug selection by a real world survey and to discuss relevant recognition factors so as to promote the implementation of generic drug policy. Methods： The questionnaire was designed referring to the relevant literature and released on-line with the Questionnaire Star （WJX） app. All data were statistically processed with SPSS. Results： A total of 294 valid questionnaires were collected and the effective rate of the questionnaire was 100%. In all the questionnaires respondents， 89 were medicalpharmaceutical laymen， 205 were in the medical-pharmaceutical profession. Among all respondents， more than half of the respondents （50.34%） worried that the drug prices were too low to guarantee the quality of drugs after the implementation of the generic drug policy. The majority of the public supported domestic generic drugs， but preferred to choose the original drugs when encountering major diseases. Conclusion： It is necessary to carry out scientific education on rational drug use of domestic generic drugs in order to eliminate the publics misunderstanding of the quality and efficacy of generic drugs and deepen the publics recognition of the domestic generic drug policy.

KEY WORDS drug price； generic drug； original drug； consistency evaluation； recognition

根據WHO调查报告，全球范围内各国药品费用支出的增速普遍高于卫生费用总支出和该国GDP的增速，控制药品费用成为降低卫生费用支出的重要措施。对我国相关省份原研药与仿制药价格比较研究显示，仿制药比相应的原研药价格低20%～90%，在控制药品费用支出方面作用显著[1]。国家实施药品集中招标和带量采购政策以来，仿制药使用强度大幅增加，原研药使用数量明显下降，患者的药品费用支出明显减少[2]，国家医保资源得到了更加合理有效的配置。2015年《国家药品安全“十二五”规划》提出药物一致性评价，要求仿制药品要与原研药品质量和疗效一致[3]。……