黎萍

摘 要 目的：探讨支气管扩张-慢性阻塞性肺疾病重叠综合征（BCOS）患者不良情绪的影响因素及与生活质量的关系。方法：选取首诊支气管扩张的BCOS患者为A组，首诊慢性阻塞性肺疾病的BCOS患者为B组，慢性阻塞性肺疾病患者为C组，支气管扩张患者为D组，每组20例。收集疾病严重程度、呼吸困难程度及焦虑抑郁分数和EORTC QLQ-C30（V3.0）生活質量调查问卷。分析BCOS患者不良情绪的影响因素及与生活质量的关系。结果：文化程度、病情严重程度为BCOS患者不良情绪的影响因素；SAS、SDS评分与整体生活质量和功能领域评分呈负相关；SAS、SDS评分与症状领域和各单项测量项目评分呈正相关（P<0.05）。结论：文化程度、病情严重程度为BCOS患者不良情绪的相关影响因素，且与生活质量有关。

关键词 支气管扩张-慢性阻塞性肺疾病重叠综合征 焦虑抑郁 生活质量

中图分类号：R563 文献标志码：B 文章编号：1006-1533（2021）15-0040-03

Negative influencing factors in patients with BCOS and their relationship with quality of life

LI Ping

（Department of Respiratory Medicine， the Peoples Hospital of Yichun City， Yichun 336000， China）

ABSTRACT Objective： To explore the influencing factors of bad mood in patients with bronchiectasis-chronic obstructive pulmonary disease （COPD） overlap syndrome （BCOS） and their relationship with the quality of life. Methods： Twenty BCOS patients who were first diagnosed as bronchiectasis were prospectively selected as group A， 20 BCOS patients who were first diagnosed as COPD as group B， 20 patients with COPD as group C， 20 patients with bronchiectasis as group D. The severity of disease， degree of dyspnea， anxiety and depression scores and EORTC QLQ-C30 （V3.0） quality of life questionnaire were collected. The influencing factors of bad mood and their relationship with quality of life in patients with BCOS were analyzed. Results： Education level and severity of illness were the influencing factors of bad mood in BCOS patients. The scores of SAS， SDS were negatively correlated with overall quality of life and functional domain scores， while were positively correlated with the scores of symptom domain and individual measurement items. Conclusion： Education level and disease severity are the related influencing factors of bad mood in patients with BCOS and are related to the quality of life.

KEY WORDS bronchiectasis-chronic obstructive pulmonary disease overlap syndrome； anxiety and depression； quality of life

支气管扩张-慢性阻塞性肺疾病重叠综合征（bronchiectasis-chronic obstructive pulmonary disease overlap syndrome，BCOS）是指患者同时存在支气管扩张和慢性阻塞性肺疾病，临床治疗的困难程度不仅较单纯支气管扩张和单纯慢性阻塞性肺疾病高，且病死等不良结局发生风险相对较高。大部分BCOS患者由于疾病等多种原因存在焦虑抑郁等不良情绪，导致治疗依从性降低，免疫功能减弱，进一步加重病情，同时可对患者的生活质量产生较大影响。因此，尽早评估BCOS患者焦虑、抑郁等情绪，并对可能导致焦虑、抑郁的因素进行分析，对指导早期干预、改善患者不良心理状态有积极意义。

1 资料与方法

1.1 一般资料

选取2019—2020年在宜春市人民医院治疗的20例首诊支气管扩张的BCOS患者作为A组，20例首诊慢性阻塞性肺疾病的BCOS患者作为B组，20例慢性阻塞性肺疾病患者作为C组，20例支气管扩张患者作为D组。……