添加益生菌治疗对48例超高龄人群胃肠动力障碍疗效研究
2021-09-07吴洁初瑮荣梁蝶刘政牟晨宇
吴洁 初瑮荣 梁蝶 刘政 牟晨宇



摘 要 目的:探究超高龄人群胃肠动力障碍治疗中添加益生菌治疗的临床效果。方法:选择96例超高龄胃肠动力障碍患者依据治疗方法不同分为对照组和观察组各48例。对照组实施肠内营养治疗,观察组添加益生菌治疗。比较两组患者临床疗效及营养生化水平情况。结果:观察组治疗有效率显著高于对照组(87.5% vs 62.5%,P<0.05);观察组白蛋白、前白蛋白和转铁蛋白分别是(43.2±11.3)g/L、(232.5±40.2)μg/mL和(322.1±50.3)ng/mL均明显高于对照组的(40.1±10.6)g/L、(192.2±40.4)μg/mL和(274.7±50.8)ng/mL(P<0.05)。结论:相比于常规肠内营养治疗,添加益生菌治疗能够有效改善患者胃肠功能,提高营养生化水平,综合治疗效果更显著。
关键词 益生菌治疗 超高龄 胃肠动力障碍 疗效
中图分类号:R975; R592 文献标志码:B 文章编号:1006-1533(2021)15-0019-02
Effect of probiotic treatment on gastrointestinal motility disorders in 48 cases of ultra-elderly population
WU Jie, CHU Lirong, LIANG Die, LIU Zheng, MOU Chenyu
(Department of Geriatrics, the Central Hospital of Nanjing, Nanjing 210018, China)
ABSTRACT Objective: To explore the clinical effect of probiotics in the treatment of gastrointestinal dyskinesia in the elderly. Methods: Ninty-six patients with gastrointestinal dyskinesia were divided into control group (48 cases) and observation group (48 cases). The control group was treated with enteral nutrition and the observation group was treated with probiotics. The clinical curative effect and the level of nutrition and biochemistry were compared between the two groups. Results: The effective rate of the observation group was significantly higher than that of the control group (87.5% vs 62.5%, P<0.05). Albumin, prealbumin and transferrin (43.2±11.3) g/L, (232.5±40.2) μg/mL and (322.1±50.3) ng/mL in the observation group were significantly higher than those in the control group (40.1±10.6) g/L, (192.2±40.4) μg/mL and (274.7±50.8) ng/mL(P<0.05), respectively. Conclusion: Compared with routine enteral nutrition therapy, probiotic therapy can effectively improve gastrointestinal function and biochemical level of nutrition, and the comprehensive treatment is more effective.
KEY WORDS probiotics treatment; ultra-elderly; gastrointestinal dysmotility; efficacy
胃肠动力障碍是超高龄人群(≥90岁)的常见胃肠疾病,对老年患者正常生活影响较大。从临床来看,超高龄人群胃肠功能障碍的发生会导致患者出现不同程度的营养不良,饮食和排便功能较差。在传统治疗中,肠内营养疗法使用广泛,但治标不治本,多是短期胃肠功能及营养水平的改善,对于提高胃肠动力功能的效果不明顯[1]。当前,益生菌疗法在胃肠动力障碍中得到良好的临床应用效果。本文以96例高龄胃肠动力障碍患者作为研究对象,探究超高龄人群胃肠动力障碍治疗中添加益生菌治疗的临床效果,现报道如下。
1 资料与方法
1.1 一般资料
选取我院2019年1月—2020年10月收治的96例超高龄胃肠动力障碍患者,诊断标准参照《多脏器功能失常综合征(multiple organ dysfuction syndrome, MODS)病情分期诊断及严重程度评分标准》。按照不同治疗方法分为对照组和观察组各48例。观察组:男30例,女18例,年龄90~95岁,平均(91.7±0.4)岁。对照组:男28例,女20例,年龄91~97岁,平均(91.5±0.6)岁。两组患者一般资料无统计学差异(P>0.05),具有可比性。……p>
