综合管理对稳定期慢性阻塞性肺疾病患者的运动能力及肺功能的影响
2021-06-02郭静魏丽娟
郭静 魏丽娟


【摘要】 目的:长期综合管理对稳定期慢性阻塞性肺疾病(COPD)患者的运动能力及肺功能的影响。方法:选取2016年6月-2017年6月于本院就诊的200例稳定期COPD患者,进行3年综合管理干预。比较干预前后运动能力及肺功能情况。结果:共163例完成了3年综合管理干预。干预后每日总能量消耗(TDEE)、活动能量消耗(AEE)、运动能力水平系数(PAL)、每天中等活动的分钟数(MMA)、每天的步数(STEPS)及6 min步行距离(6MWD)均优于干预前,差异均有统计学意义(P<0.05)。干预后,第1秒用力呼气容积(forced expiratory volume in the first second,FEV1)、FEV1/用力肺活量(forced vital capacity,FVC)及圣乔治呼吸问卷(SGRQ)评分均优于干预前,差异均有统计学意义(P<0.05)。结论:长期综合管理可有效改善稳定期COPD患者的运动能力及肺功能,进而提升患者的生活质量,值得临床应用。
【关键词】 慢性阻塞性肺疾病 稳定期 综合管理 运动能力
[Abstract] Objective: To investigate the effects of long-term comprehensive management on exercise ability and lung function in patients with stable chronic obstructive pulmonary disease (COPD). Method: A total of 200 patients with stable COPD admitted to our hospital from June 2016 to June 2017 were selected for 3-year comprehensive management intervention. Exercise ability and lung function were compared before and after intervention. Result: A total of 163 cases completed the 3-year comprehensive management intervention. After intervention, total daily energy expenditure (TDEE), activity energy expenditure (AEE), physical activity level (PAL), daily minutes of moderate activity (MMA), daily steps (STEPS) and 6 min walking distance (6MWD) were better than those before intervention, with statistical significance (P<0.05). After the intervention, forced expiratory volume in the first second (FEV1), FEV1/forced vital volume capacity (FVC) and St. Georges respiratory questionnaire (SGRQ) scores were better than those before intervention, with statistically significant differences (P<0.05). Conclusion: Long-term comprehensive management can effectively improve the exercise ability and lung function of stable COPD patients, and then improve the quality of life of patients, which is worthy of clinical application.
[Key words] Chronic obstructive pulmonary disease Stable period Comprehensive management Exercise ability
First-authors address: Beijing Sixth Hospital, Beijing 100007, China
doi:10.3969/j.issn.1674-4985.2021.11.043
慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)是一種以气流受限为特征的衰弱性疾病,通常是持续进行性的[1-2]。运动性呼吸困难是COPD的主要症状之一,导致患者日常生活中运动能力受限,缺乏必要的运动是住院和死亡率的重要预测因子,也可能是COPD合并症的关键环节[3]。研究显示,COPD患者不仅肺功能下降,而且心功能障碍、全身炎症和肌肉无力等多种全身性疾病都与运动能力下降有关[4-5]。对稳定期COPD患者进行合理有效的综合性管理干预,对其改善症状,提高运动能力及生活质量具有重要意义。本研究探讨了长期综合管理对稳定期COPD患者运动能力与肺功能的影响,现报道如下。
1 资料与方法
1.1 一般资料 选取2016年6月-2017年6月于本院就诊的200例COPD患者。纳入标准:符合全球慢性阻塞性肺病倡议(GOLD)中稳定期COPD的诊断标准,反复咳嗽咳痰、胸闷、气促,桶状胸,双肺可闻及哮鸣音或湿啰音;影像学检查胸部CT或DR检查有肺气肿;吸入支气管扩张剂后……
