婚检孕检中乙肝标志物的应用价值分析
2021-02-03杨健
杨健
【摘 要】目的:探讨在婚前检查、孕前检查中,乙肝标志物的应用价值。方法:选入在2019年7月至2021年7月间,进行婚前检查、孕前检查的人群总计5531例,以回顾性分析的形式记录检查结果、不同性别受检人员感染率。结果:5531例检查人群,684例阳性,其中206例谷丙转氨酶ALT指数上升,HBsAg、HBeAg、抗HBC三项阳性28.51%,HBsAg、HBeAb、抗HBC三项阳性55.56%;男性感染率12.97%相对高于女性9.41%,差异有统计学意义(P<0.05)。结论:在婚前检查以及孕前检查中,进行乙肝标志物的测定,有助于对受检人员健康情况进行了解,从而进一步认识到乙肝病毒具有的危害性特征,从而强化乙肝疾病的宣传和专业预防。
【关键词】婚前检查;孕前检查;乙肝标志物;应用价值
Analysis of the application value of hepatitis B markers in pre-marital pregnancy examination
Yang Jian
Guilin Maternal and Child Health Care Hospital, Guilin Guangxi 541001, China
【Abstract】Objective:To explore the application value of hepatitis B markers in premarital examination and pre pregnancy examination. Methods: A total of 5531 people who underwent premarital examination and pre-pregnancy examination between July 2019 and July 2021 were selected, and recorded the examination results and infection rate of subjects with different sexes in the form of retrospective analysis. Results: Among 5531 cases examinged, 684 cases were positive, of which 206 cases had increased ALT index, 28.51% were positive for HBsAg, HBeAg and antiHBC and 55.56% were positive for HBsAg, HBeAb and antiHBC; male infection rate was 12.97% relatively higher than 9.41% in women, statistically significant (P<0.05).Conclusion:In the premarital examination and pre-pregnancy examination, the determination of hepatitis B markers is helpful to understand the health of the people examined, so as to further realize the harmful characteristics of hepatitis B virus, and thus strengthening the publicity and professional prevention of hepatitis B disease.
【Key?Words】Premarital examination; Pre-pregnancy examination; Hepatitis B markers; Application value
根據目前临床不完全统计[1],我国是乙型肝炎的高发区,临床乙肝病毒的测定主要为乙肝病毒定性、定量、基因分型和耐药变异的测定。且母婴传播也是小儿艾滋病、梅毒和乙肝的主要传染途径,从我国开展孕检和婚检工作以来,已经形成了十分完善的孕前检查工作,因此早期发现患有艾滋病、梅毒和乙肝孕妇,同时予以对症干预,能够有效阻断母婴传播[2]。在婚前检查中实施乙肝标志物测定,有利于减少乙肝在两性之间的传播。基于此,本文将分析在婚检孕检中乙肝标志物的应用价值。
1.1 基本数据
在2019年7月至2021年7月,该院进行婚前检查、孕前检查的人群总计5531例,其中男性2766例,女性2765例,年龄23岁~32岁,平均年龄(25.68±1.82)岁。
1.2 方法
提取受检人员的空腹静脉血,共计2管,一管2mL,一管5mL;对血清标本提取后,对乙型肝炎病毒指标、丙氨酸氨基转移酶测定。……
