谢彩霞

【摘 要】目的：研究西格列汀联合二甲双胍治疗2型糖尿病的临床效果。方法：选择治疗时间为2017年10月至2018年10月之间的患者人数为60例，通过进行小组划分方式来区分治疗，分为对照组与观察组，其中观察组采用西格列汀联合二甲双胍进行治疗，遵医嘱服用，对比两组的并发症与治疗效果。结果：研究结果表明，观察组整体并发症发生率低于对照组，整体疗效比对照组好（P<0.05）。结论：在临床上，治疗2型糖尿病患者可以选择采用西格列汀配合二甲双胍药物，效果显著，可以在临床上广泛推广应用。

【关键词】西格列汀；二甲双胍；2型糖尿病；临床观察

Clinical observation of sitagliptin combined with metformin in the treatment of type 2 diabetes

Xie Caixia

Qingtongxia People’s Hospital， Qingtongxia Ningxia 751600， China

【Abstract】Objective： To study the clinical effect of sitagliptin combined with metformin in the treatment of type 2 diabetes. Method： 60 patients with treatment time from October 2017 to October 2018 were selected. The treatment was divided into a control group and an observation group by group division. The observation group was treated with sitagliptin combined with metformin and took it as ordered by the doctor.The complications and treatment effects of the two groups were compared. Results： The results of the study showed that the overall complication rate of the observation group was lower than that of the control group， and the overall curative effect was better than that of the control group. Conclusion： In clinical treatment， sitagliptin combined with metformin can be chosen to treat patients with type 2 diabetes， which has significant effects and can be widely used in clinical practice.

【Key？Words】Sitagliptin； Metformin； Type 2 diabetes； Clinical observation

在糖尿病的患病中，每年患有糖尿病患者中，大約有百分之八十九的患者是属于2型糖尿病情况[1]。伴随着生活水平的不断提升，患有糖尿病情况的患者人数也随之开始增多。糖尿病是一种临床代谢性疾病，通过持续性高血糖作为临床特征，其具体发病尚未研究明确[2]。现有研究表明胰岛素的分泌缺陷是由于病理、生理等多方面因素所导致的。发生胰岛素下降情况进一步造成代谢紊乱。因此可以表明出现糖尿病症状可跟胰岛素分泌进行联系[3]。

1 资料与方法

1.1 一般资料

选择治疗时间为2017年10月至2018年10月之间的患者人数为60例，通过进行小组划分方式来区分治疗。观察组，男性13例，女性17例，年龄59岁～72岁，平均年龄（65.35±4.39）岁；对照组，男性18例，女性12例，年龄61岁～74岁，平均年龄（65.35±4.39）岁。两组在一般资料对比上差异不明显（P>0.05），可进行临床对比。……