曹春杰

【摘 要】 目的：探讨对子痫前期孕产妇进行血清尿素氮、肌酐、尿酸等指标检测的临床价值。方法：2016年7月至2019年2月，选取本院诊治的子痫前期患者共计80例，其中轻度子痫前期患者40例，重度子痫前期患者40例，并选取同期30例正常妊娠孕妇，然后检测各组的血清尿素氮、肌酐、尿酸指标。结果：检测结果显示，三组人群血清尿素氮、肌酐、尿酸等肾功能指标比较，轻度子痫前期组各项检测指标均低于重度子痫前期组（P<0.01）;同时均高于正常妊娠组（P<0.01）。结论：对子痫前期患者肾功能损害程度的临床诊断，血清尿素氮、肌酐、尿酸等指标的检测具有重要的临床应用价值。

【关键词】 孕产妇;子痫前期;肾功能指标;临床意义

The clinical value of serum urea nitrogen， creatinine， uric acid and other indicators in pregnant women with preeclampsia

Cao ChunJie

People's Hospital in Jiaxiang County of Shandong Province， Jining ， Shandong 272400

[Abstract] Objective：To explore the clinical value of serum urea nitrogen， creatinine， uric acid and other indicators in pregnant women with preeclampsia. Methods： From July 2016 to February 2019， a total of 80 cases of preeclampsia patients were selected from our hospital， including 40 cases of mild preeclampsia patients and 40 cases of severe preeclampsia patients.30 normal pregnant women were selected during the same period， and then the indexes of serum urea nitrogen， creatinine and uric acid in each group were tested. Results： The test results showed that the renal indexes of serum urea nitrogen， creatinine and uric acid in the three groups were lower in the mild preeclampsia group than in the severe preeclampsia group （P<0.01）; All of them were higher than normal pregnancy group （P<0.01）. Conclusion： The detection of serum urea nitrogen， creatinine and uric acid has important application value for the clinical diagnosis of renal impairment in patients with preeclampsia.

[Key words]Maternal; Preeclampsia; Renal function index; The clinical value

子癇前期为孕产妇妊娠期的特有疾病之一，临床上常常伴有终末器官损害等严重并发症，目前认为是血管痉挛和内皮活化所致器官灌注减少导致疾病的发生。子痫前期是妊娠期特有疾病和常见的并发症之一，严重威胁着广大母婴的健康，是导致孕产妇和围生儿疾病和死亡的重要原因之一。此种疾病诱发特征就是高血压以及蛋白尿等，会对她们全身构成器官功能性损伤乃至最终的衰竭;更有严重的会产生昏迷现象与抽搐现象，亦或者诱发死亡事件。目前来说，对于子痫前期孕产妇选择终止妊娠的方案成为临床治疗的关键举措。但是，子痫前期最大的影响就是会损伤她们的终末器官[1]。所以，准确评价其损伤程度能够更准确的进行适宜分娩时间的选择，从而实现母婴结局改善目标[2]。鉴于检测优势，借助现在检测条件完成测定工作以及指标间的比较，本研究对嘉祥县人民医院诊治的80例子痫前期孕产妇和同期30例正常妊娠孕妇完成血清尿素氮、肌酐、尿酸等肾功能生化相关指标进行检测，现将有关检测结果分析报道如下。……