王朝晖　赵云红　范冬连

【摘要】 目的：浅析慢性阻塞性肺疾病合并肺部感染患者治疗中盐酸氨溴索的应用效果。方法：此次100例试验研究对象全是笔者所在医院2016年6月-2018年11月收治的慢性阻塞性肺疾病合并肺部感染患者，分组标准为信封抽签法，每组50例，治疗中分别行常规治疗（对照组）和常规治疗+盐酸氨溴索治疗（试验组），对比两组治疗效果。结果：试验组和对照组患者临床总有效率分别为94.00%、78.00%，差异有统计学意义（P<0.05）。在发热、肺部啰音、胸闷气促、咳嗽等典型症状恢复时间上，试验组均短于对照组，且试验组住院时间短于对照组，差异均有统计学意义（P<0.05）。结论：盐酸氨溴索在慢性阻塞性肺疾病合并肺部感染患者治疗中具有良好的应用效果，能有效缩短病症恢复时间，让患者更快康复出院，临床中值得全方位推广。

【关键词】 慢性阻塞性肺疾病; 肺部感染; 盐酸氨溴索

doi：10.14033/j.cnki.cfmr.2019.16.058 文献标识码 B 文章编号 1674-6805（2019）16-0-03

【Abstract】 Objective：To analyze the application effect of Ambroxol Hydrochloride in the treatment of patients with chronic obstructive pulmonary disease and pulmonary infection.Method：The 100 subjects of the study were all patients with chronic obstructive pulmonary disease and pulmonary infection who were admitted between June 2016 and November 2018.The standard for grouping were envelope lottery，50 cases in each group.Routine treatment（the control group） and routine treatment+Ambroxol Hydrochloride treatment（the experimental group） were given in the treatment.The therapeutic effects of the two groups were compared.Result：The total effective rate of the experimental group and the control group was 94.00% and 78.00%，and the difference was statistically significant（P<0.05）.In the recovery time of typical symptoms such as fever，lung rales，chest tightness and shortness of breath，cough，etc.，the experimental group were shorter than the control group，and the length of hospital stay in the experimental group was shorter than that in the control group，the differences were statistically significant（P<0.05）.Conclusion：Ambroxol Hydrochloride has a good application effect in the treatment of patients with chronic obstructive pulmonary disease and pulmonary infection.It can effectively shorten the recovery time of the disease and allow patients to recover faster.It is worthy of comprehensive promotion in clinical practice.

【Key words】 Chronic obstructive pulmonary disease; Pulmonary infection; Ambroxol Hydrochloride

First-authors address：Nanxiong Hospital of Traditional Chinese Medicine，Nanxiong 512400，China

在呼吸系统疾病中慢性阻塞性肺疾病是比较严重且破坏性较强的一种疾病，老年人患病率较高，而且长期吸烟的男性患病率高于女性。近些年来，全球范围内越来越多的慢性阻塞性肺疾病患者合并出现肺部感染情况，在所有患者中约占10%，而70岁以上的患者中約占33%，这也成为导致老年人死亡的主要疾病[1]。由于患者气道阻塞，为了改善肺功能，首先要疏通气道，再配合抗感染等治疗。盐酸氨溴索属于祛痰药物，能有效缓解呼吸道阻塞情况[2]。笔者所在医院为了进一步证实盐酸氨溴索的应用效果，筛选100例患者为试验对象进行本次研究，详情报道如下。

1 资料与方法

1.1 一般资料

选取笔者所在医院2016年6月-2018年11月收治的100例慢性阻塞性肺疾病合并肺部感染患者作为试验对象。纳入标准：满足《慢性阻塞性肺疾病诊治指南》的诊断标准[3];均存在咳痰、咳嗽、气促、喘憋、呼吸困难等表现;听诊有湿啰音，X线检查肺部纹理增粗、增多。……