蔡龙

【摘要】 目的：探讨腔静脉滤器联合置管溶栓治疗急性下肢深静脉血栓。方法：研究人员随机抽取2016年3月-2018年2月来院就诊的120例急性下肢深静脉血栓患者，所有的患者均为自愿参与且符合纳入标准，采用随机系统将患者均分为对照组与观察组，对照组患者接受外周抗凝溶栓治疗，观察组患者接受腔静脉滤器联合置管溶栓治疗，根据患者的大腿及小腿消肿率、大腿及小腿周径差、介入治疗效果评估本次研究的临床效果。结果：治疗后，观察组患者的大腿及小腿周径差均小于对照组，且观察组患者的大腿及小腿消肿率均高于对照组，观察组患者的溶栓持续时间及住院时长均短于对照组，差异均有统计学意义（P<0.05）。结论：急性下肢深静脉血栓患者接受腔静脉滤器联合置管溶栓治疗效果显著。

【关键词】 腔静脉滤器; 置管溶栓; 急性下肢深静脉血栓

doi：10.14033/j.cnki.cfmr.2019.16.019 文献标识码 B 文章编号 1674-6805（2019）16-00-02

【Abstract】 Objective：To investigate the effect of vena cava filter combined with catheter thrombolysis on acute deep venous thrombosis of lower extremity.Method：120 patients with acute deep venous thrombosis of lower extremity who came to our hospital from March 2016 to February 2018 were randomly selected.All patients were voluntary participants and met the criteria of admission and did not meet the exclusion criteria.The patients were randomly divided into the control group and the observation group.The patients in the control group were treated with peripheral anticoagulant thrombolytic therapy，and the patients in the observation group were treated with vena cava filter combined with catheter thrombolysis.The clinical effect of this study was evaluated according to the patient's thigh and calf detumescence rate，the difference of thigh and calf circumference，and the effect of interventional therapy.Result：The difference of thigh and calf circumference in the observation group were smaller than those in the control group，and the rate of thigh and calf detumescence in the observation group were higher than those in the control group.The duration of thrombolysis and length of hospitalization in the observation group were shorter than those in the control group，the differences were statistically significant（P<0.05）.Conclusion：The treatment of acute deep venous thrombosis of lower extremity with vena cava filter combined with catheter thrombolysis is effective.

【Key words】 Vena cava filter; Catheter thrombolysis; Acute deep venous thrombosis of lower extremity

First-authors address：Xiaogan Central Hospital，Xiaogan 432000，China

下肢靜脉血栓疾病患者会出现下肢疼痛、肿胀及代谢性浅静脉曲张等症状，且近年来，该疾病的发病率逐渐上升。该疾病是患者自身的静脉血液在下肢深静脉血管内不正常凝结，导致阻塞静脉腔，出现静脉回流障碍，若不及时地接受治疗，患者易出现肺栓塞甚至是猝死。若不及时给予患者有效的干预措施，极易出现继发性静脉曲张、色素沉着及下肢水肿等后遗症。临床上对于急性下肢静脉血栓疾病的治疗主要是采用腔静脉滤器联合置管溶栓治疗，临床治疗效果显著[1]。为了探究该治疗方式的临床效果，特开展本次研究，现将研究结果总结报道如下。……