谷小宝

[摘要] 目的 观察盐酸氨溴索治疗慢性支气管炎的疗效及安全性。方法 方便选择2017年8月—2018年1月来该院就诊的92例慢性支气管炎患者，年龄范围51～92岁，随机分为对照组和治疗组，每组46例。对照组给予常规治疗，治疗组给予盐酸氨溴索注射液治疗，比较两组患者的治疗总有效率以及不良反应发生率。 结果 经治疗，治疗组的总有效率为93.5%，明显优于对照组的69.6%，治疗组的不良反应发生率（13.04%）与对照组相比显著降低，两组差异有统计学意义（χ2=5.678、12.056，P<0.05）。结论 在临床上，采用盐酸氨溴索注射液对治疗慢性支气管炎能够取得明显的效果，不良反应发生率较低，治疗总有效率达到90%以上，该种方法值得在各医院推广并运用。

[关键词] 盐酸氨溴索；慢性支气管炎；疗效

[中图分类号] R562 [文献标识码] A [文章编号] 1674-0742（2018）08（b）-0087-03

Therapeutic Efficacy and Safety of Ambroxol Hydrochloride in the Treatment of Chronic Bronchitis

GU Xiao-bao

Department of Emergency Medicine， First People's Hospital of Guannan County， Guannan， Jiangsu Province， 222500 China

[Abstract] Objective To observe the efficacy and safety of ambroxol hydrochloride in the treatment of chronic bronchitis. Methods A total of 92 patients with chronic bronchitis who visited the hospital from August 2017 to January 2018 were convenient selected. The age range was 51 to 92 years old and they were randomly divided into control group and treatment group with 46 patients in each group. The control group received conventional treatment. The treatment group was treated with ambroxol hydrochloride injection. The total effective rate of treatment and the incidence of adverse reactions were compared between the two groups. Results After treatment， the total effective rate was 93.5% in the treatment group， which was significantly better than 69.6% in the control group. The incidence of adverse reactions in the treatment group （13.04%） was significantly lower than that in the control group. There was a statistically significant difference between the two groups（χ2=5.678，12.056，P<0.05）. Conclusion Clinically， the use of Ambroxol hydrochloride for the treatment of chronic bronchitis can achieve significant results， the incidence of adverse reactions is low， and the total effective rate of treatment reaches more than 90%. This method is worthy of promotion and application in all hospitals.

[Key words] Ambroxol hydrochloride； Chronic bronchitis； Efficacy

慢性支氣管炎（chronic bronchitis，CB）在临床诊断中，主要特点是咳痰和慢性咳嗽，临床检测也可表现为黏液分泌增多等炎性反应。该病好发于男性，慢性支气管炎的发病原因有多种，吸烟作为该疾病的首要原因，其次由于吸入空气污染物造成的呼吸道堵塞[1]，此外，病毒、细菌等微生物的感染也是慢性支气管炎发展的一个重要原因。慢性支气管炎作为一种常见疾病，其对机体的损害不容忽视，采取积极有效的预防和治疗手段有积极作用。目前在临床上多为药物治疗。该次研究方便选取2017年8月—2018年1月来该院就诊的92例慢性支气管炎患者作为研究对象，探究盐酸氨溴索治疗慢性支气管炎的疗效及安全性。现报道如下。

1 资料与方法

1.1 一般资料

选择来该院就诊的92例慢性支气管炎患者，年龄范围51～92岁，平均年龄（54.23±34.66）岁，其中男患者65例，女患者27例，随机分为对照组和治疗组。……