张煜 李婧昳 卓嘎 李傅尧 戴宁 仁青加 李峰

[摘要] 变应性疾病患者的数量会随着经济的繁荣而高速增长，其中变应性鼻炎迁延日久可发展成变应性哮喘，进而诱发过敏性休克，危及生命。因此有效治疗变应性鼻炎、阻断其进程，可预防变应性哮喘等很多疾病的发生。目前西医的药物治疗主要是对症治疗，不能有效阻止变应性鼻炎的复发和疾病的进程；免疫治疗针对过敏原，可以治本，但有很多过敏原尚未开发出免疫制剂且过敏原种类不胜枚举。因此，变应性鼻炎的中医药治疗尤其值得研究。从变应性鼻炎的中医病因病机入手，利用天然药物中芳香药物的化痰湿、理气活血、开窍、宣透通络等功效，厘清香药治疗变应性鼻炎的作用机制，进而开展香药治疗变应性鼻炎的有效成分、作用靶标及疗效通路的研究，为治疗变应性鼻炎新药物、新剂型的开发研究奠定基础。

[关键词] 香药；变应性鼻炎；诊断；治疗

[中图分类号] R276.152.1 [文献标识码] A [文章编号] 1673-7210（2018）04（a）-0099-03

[Abstract] The number of patients with allergic diseases will grow rapidly with the prosperity of the economy， in which allergic rhinitis can develop into allergic asthma， induce anaphylactic shock， and then endanger life. Therefore， effective treatment of allergic rhinitis and blocking the process can prevent the occurrence of allergic asthma and many other diseases. At present， drug treatment in western medicine is mainly symptomatic treatment， but the recrudescence of allergic rhinitis and the process of disease can not be effectively prevented； immunotherapy for allergies can be used as a cure， but there are many allergies that have not developed immune agents and the variety of allergies is too numerous to enumerate. Therefore， the Chinese medicine treatment of allergic rhinitis is especially worthy of research. Starting from the etiology and pathogenesis of allergic rhinitis， utilize aromatic drugs in natural drugs to reduce phlegm dampness， regulate qi and activate blood， open the orifices and spread the collaterals， clarify the mechanism of the treatment of allergic rhinitis， and then carry out the study on the effective components of medicinal herbs in the treatment of allergic rhinitis， action target and therapeutic pathway， and lay the foundation for the development and research of new drugs and new dosage forms for allergic rhinitis.

[Key words] Aromatic drugs； Allergic rhinitis； Diagnosis； Treatment

变应性鼻炎又称过敏性鼻炎或变态反应性鼻炎，是过敏性疾病的一种。全世界有22%～40%人口被过敏问题困扰，且生活在经济发达地区的人更易罹患过敏性疾病[1]，我国正经历过敏性疾病患者数量不断增长的过程。变应性鼻炎迁延日久可发展至哮喘，进而诱发过敏性休克，危及生命[2]。因此有效治疗变应性鼻炎、阻断其进程是迫切需要解决的问题。西医治疗变应性鼻炎有对症的药物治疗和对因的免疫治疗。……