同型半胱氨酸、超敏C—反应蛋白含量与颈动脉内中膜厚度联合检测在冠心病患者中的应用效果分析
2018-03-07吴秋银
吴秋银
[摘要] 目的 探讨同型半胱氨酸(HCY)、超敏C-反应蛋白(Hs-CRP)含量与颈动脉内中膜厚度(IMT)联合检测在冠心病患者中的应用效果。方法 方便选取至该院就诊的150例冠心病患者(2014年2月—2017年2月)设置为实验组,另外同期选择150名健康体检人群设置为常规组,分析不同分组的HCY、Hs-CRP、IMT。结果 实验组HCY、Hs-CRP、IMT检测值分别为(20.58±5.33)μmol/L、(11.59±5.30)mg/L、(1.35±0.40)mm,相比常规组均明显较高(P<0.05);AMI患者的HCY、Hs-CRP、IMT检测值分别为(20.63±3.10)μmol/L、(16.98±2.88)mg/L、(1.61±0.35)mm,相比其他两组均明显较高(P<0.05),UAP患者的HCY、Hs-CRP检测值分别为(17.30±3.25)μmol/L、(13.61±3.15)mg/L,相比SAP患者均明显较高(P<0.05)。结论 HCY、Hs-CRP水平与冠心病患者的病情息息相关,随着患者病情的加剧,其检测值将会递增,便于为疾病的诊断提供相关的依据。
[关键词] 同型半胱氨酸;超敏C-反应蛋白;颈动脉内中膜厚度;冠心病
[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742(2017)12(b)-0042-03
[Abstract] Objective To study the application effect of combined test of homocysteine, High sensitive C-reactive protein and carotid intima-media thickness in patients with coronary heart disease. Methods 150 cases of patients with coronary heart disease diagnosed in our hospital from February 2014 to February 2017 convenient selected were selected as the experimental group, while 150 cases of healthy physical examination people at the same period were selected as the routine group, and the HCY, Hs-CRP, IMT of each group were analyzed. Results The HCY, Hs-CRP, IMT test values in the experimental group were respectively (20.58±5.33)μmol/L,(11.59±5.30)mg/L,(1.35±0.40)mm, which were obviously higher than those in the control group(P<0.05), and the HCY, Hs-CRP, IMT test values of AMI patients were respectively (20.63±3.10)μmol/L, (16.98±2.88)mg/L, (1.61±0.35)mm, which were obviously higher than those in the other two groups(P<0.05), and the HCY, Hs-CRP of UAP patients were respectively (17.30±3.25)μmol/L,(13.61±3.15)mg/L, which were obviously higher than those of SAP patients(P<0.05). Conclusion The HCY and Hs-CRP levels are closely related to the diseases of patients with coronary heart disease, with the increase of the disease, the test value is increasing, and it can provide relevant basis for the diagnosis of diseases.
[Key words] Homocysteine; Hypersensitive c-reactive protein; Carotid intima-media thickness; Coronary heart disease
隨着近些年来生活水平的提高与经济的发展,导致心血管疾病的发病率、死亡率均逐渐递增[1]。有关研究指出[2],目前全球每年死于心血管疾病的患者达到1 700万人次,而我国现存的心血管疾病患者已经超过了2.3亿人次,其死亡率较高,导致对患者的身体健康与生命安全造成了严重的威胁,所以说,加强相关的疾病预防措施,将心血管疾病的发生发展进行有效控制刻不容缓,便于将公民的健康水平进一步提高。对于冠心病患者进行有效预防的关键内容为对各个危险因素进行控制,心血管疾病的危险因素多种多样,包括高血脂、高血压、糖尿病、肥胖、饮酒、吸烟、缺乏运动、不良饮食习惯、心理因素、社会因素、遗传因素等,积极对上述危险因素进行控制,便于降低疾病的死亡率,但是仍然存在一定的潜在文献因素。有关研究指出,对冠心病患者进行相关指标的检查意义重大。该次研究收治了2014年2月—2017年2月来该院就诊的150例冠心病患者与150名健康体检者,并对其同型半胱氨酸、超敏C-反应蛋白含量与颈动脉内中膜厚度进行联合检测,分析其检测意义,现报道如下。……
