胡辉苑?彭艳

[摘要] 目的 探讨间苯三酚对妊娠20周前先兆流产的效果分析。 方法 随机抽取我院自2014年1月～2016年1月收治的80例妊娠20 周前先兆流产患者，分为实验组、对照组，各40例。对照组进行硫酸镁治疗，实验组进行间苯三酚治疗。对比两组的总有效率、起效时间、宫缩缓解时间以及不良反应发生率。 结果 实验组患者的总有效率95.0%远高于对照组患者的77.5%，起效时间、宫缩缓解时间远短于对照组患者，不良反应发生率为2.5%远低于对照组患者的20.0%，差异有统计学意义（P<0.05）。 结论 间苯三酚在治疗妊娠20 周前先兆流产取得的临床效果显著，且不良反应发生率较低，值得进一步推广和使用。

[关键词] 间苯三酚；妊娠20周前；先兆流产

[中图分类号] R714.21 [文献标识码] A [文章编号] 2095-0616（2017）16-78-03

Clinical analysis of phloroglucin in treatment of threatened abortion after 20 weeks gestation

HU Huiyuan PENG Yan

Department of Gynaecology，Zhongkai Peoples Hospital，Huizhou 516229，China

[Abstract] Objective To explore the effect of phloroglucin in treatment of threatened abortion 20 weeks after gestation. Methods 80 cases of threatened abortion 20 weeks after gestation cured in our hospital from January 2014 to January 2016 were randomly selected and divided into experimental group and control group with 40 cases in each.Patients in control group were treated with magnesium sulphate，and patients in experimental group were treated with phloroglucin.The total effective rate，onset time，contraction time and adverse reaction rate of the two groups were compared. Results The total effective rate of the experimental group 95% was much higher than that of the control group 77.5%.The onset time and the time of contraction relief were much shorter than those in the control group.The rate of good reaction 2.5% was much lower than that of the control group 20%.The difference was significant （P<0.05）. Conclusion Clinical effect of phloroglucin in treatment of threatened abortion 20 weeks after gestation is remarkable.And the incidence of adverse reactions is low.It is worth further promotion and use.

[Key words] Phloroglucin；20 weeks after pregnancy；Threatened abortion

先兆流产是临床上常见的一种妇科疾病，发生在妊娠的第12～28周，患者常见的临床表现为：阴道流血、下腹痛或腰酸。紧缩以及不规则下腹部疼痛等[1]。据调查显示：对于孕20周前先兆流产的患者，給予间苯三酚治疗，有效缓解了患者临床症状，发生不良反应极少[2]。故随机抽取我院自2014年1月～2016年1月收治的80例妊娠20周前先兆流产患者进行深入、有效的研究，现报道如下。

1 资料与方法

1.1 一般资料

随机抽取我院自2014年1月～2016年1月收治的80例妊娠20周前先兆流产患者，分为实验组、对照组，各40例。实验组年龄22～32岁，平均（27.0±4.6）岁，其中初产妇24例、经产妇16例，孕周11～19周，平均（15.26±3.17）周。对照组年龄21～33岁，平均（27.0±4.4）岁，其中初产妇23例、经产妇17例，孕周12～19周，平均（15.59±3.68）周。本组研究中两组患者的基线资料比较，差异无统计学意义（P>0.05），具有可比性。纳入标准：（1）孕周在20周以内的患者。（2）经超声确诊为先兆流产的患者。（3）患者以及家属在治疗前均与我院签署《知情同意书》。排……