黄碧连

[摘要] 目的 研究分析无创呼吸机治疗慢性阻塞性肺疾病（COPD）合并呼吸衰竭的临床效果。 方法 从本院2015年1月～2016年10月收治的慢性阻塞性肺疾病合并呼吸衰竭患者中，选取70例患者纳入此研究领域中，按照入院顺序，单号作为对照组（n=35），双号作为观察组（n=35），对照组实施常规治疗，观察组在常规治疗基础上采用无创呼吸机治疗。 结果 （1）观察组患者的PaO2、SaO2水平高于对照组，HR、PaCO2水平低于对照组（P<0.05）；（2）观察组患者住院时间短于对照组，再入院次数少于对照组（P<0.05）；（3）观察组患者并发症发生率5.71%，明显低于对照组的22.86%（P<0.05）。 结论 慢性阻塞性肺疾病合并呼吸衰竭患者采用无创呼吸机治疗，有利于减少呼吸肌耗氧，改善呼吸肌疲劳，缩短住院时间，减少再入院次数，并发症少，安全性高，最终提高患者临床治疗效果。

[关键词] 慢性阻塞性肺疾病；呼吸衰竭；无创呼吸机；临床效果；并发症

[中图分类号] R563.9 [文献标识码] A [文章编号] 2095-0616（2017）13-186-03

[Abstract] Objective To study the clinical effect of noninvasive ventilation in the treatment of chronic obstructive pulmonary disease（Chronic obstructive pulmonary disease，COPD） in patients with respiratory failure. Methods 70 patients with chronic obstructive pulmonary disease combined with respiratory failure cured in our hospital from January 2015 to October 2016 year were enrolled in this study.According to the order of admission number，the patients with odd number were divided into control group（n=35），and patients with even number were divided into observation group（n=35）.Patients in control group were treated with routine treatment，and patients in observation group were treated with the conventional treatment based on the use of noninvasive call Suction machine treatment. Results （1）The PaO2，SaO2 levels in observation group were higher than those in control group，and HR，PaCO2 levels in observation group were lower than those in control group（P<0.05）.（2） Hospitalization time in observation group was shorter than that in control group， the readmission rate in observation gorup was less than that in control group （P<0.05）.（3）The incidence of complications in observation group was 5.71%，which was significantly lower than that of control group with 22.86%（P<0.05）. Conclusion Noninvasive ventilation in the treatment of patients with chronic obstructive pulmonary disease combined with respiratory failure can reduce respiratory muscle oxygen consumption，improve respiratory muscle fatigue，shorten hospitalization time，and reduce readmission times.It has few complications and high safety.It can improve the clinical treatment effect.

[Key words] Chronic obstructive pulmonary disease ；Respiratory failure；Noninvasive ventilator；Clinical effect； Complication

慢性阻塞性肺疾病（COPD）是呼吸內科常见病和多发病，以持续气流受限为主要特征，伴或不伴有气道高反应特征，临床表现为咳嗽、咳痰、气短、呼吸困难、胸闷、喘息等，严重影响患者生活质量。慢性阻塞性肺疾病合并呼吸衰竭时，氧疗是关键，国外有研究表明此类患者接受持续氧疗后[1]，死亡率降低了30%～40%。随着临床医疗技术的不断发展，无创正压通气在临床广泛应用，可有效控制患者病情，无需插管及应用镇静剂，患者饮食、吞咽、咳嗽等不受影响，大大提高了患者的依从性。此研究采用无创呼吸机治疗COPD合并呼吸衰竭，观察临床治疗效果，旨在为疾病治疗方案的选择提供参考依据，现报道如下。

1 资料与方法

1.1 一般资料

将2015年1月～2016年10月在我院接受治疗的70例慢性阻塞性肺疾病合并呼吸衰竭患者作为研究对象，均符合入组标准：（1）符合2013年《慢性阻塞性肺疾病诊治指南》中COPD和呼吸衰竭诊断标准[2]；……