PCT对细菌感染性疾病的作用
2017-07-01严新梅
严新梅

[摘要] 目的 探析PCT(血清降钙素原)对细菌感染性疾病的作用。方法 2015年12月—2016年12月期间该院共收治57例细菌感染患者,将其作为该次研究的观察组;另选同期所收治的57例非细菌感染患者为该次研究的对照组。对比其C反应蛋白(CRP)、以及PCT(血清降钙素原)检测结果。结果 观察组患者PCT阳性检出率为91.23%;CRP检测阳性检出率为82.46%;两项结果相比,差异无统计学意义(P>0.05)。对照组患者PCT阳性检出率为21.05%;CRP阳性检出率为70.18%;两项结果相比,差异有统计学意义(P<0.05)。在PCT检测中,对照组与观察组在阳性检出率上差异有统计学意义(P<0.05);在CRP检测中,对照组与观察组在阳性检出率上差异无统计学意义(P>0.05)。结论 PCT检测以及CRP检测均能够为细菌感染性疾病的确诊提供一定的临床依据,但就特异性而言,CRP检测远不如PCT检测。
[关键词] PCT(血清降钙素原);CRP(C反应蛋白);细菌感染性疾病;阳性率
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2017)05(a)-0044-03
[Abstract] Objective To investigate the effect of PCT (serum procalcitonin) on bacterial infectious diseases. Methods From December 2015 to December 2016, 57 patients with bacterial infection were selected as the observation group of this study. 57 patients with non-bacterial infection were treated with the same period were selected as the control group. Compared with its C-reactive protein (CRP), and PCT (serum procalcitonin) test results. Results The positive rate of PCT detection was 91.23% in the observation group and 82.46% in the CRP group. The difference was not statistically significant (P> 0.05). The positive rate of PCT detection was 21.05% in the control group and 70.18% in the CRP group. The difference was statistically significant(P<0.05). There was no significant difference in positive detection rate between the control group and the observation group(P<0.05). There was no significant difference in the positive rate of detection between the control group and the observation group(P>0.05). Conclusion PCT test and CRP test can provide some clinical basis for the diagnosis of bacterial infectious diseases, but in particular, CRP detection is far less than PCT test.
[Key words] PCT (serum procalcitonin); CRP(C-reactive protein); Bacterial infectious diseases; Positive rate
細菌感染性疾病在人类社会中颇具威胁性,是影响人们身体健康的一项重要因素,并且该类疾病在重症监护室的看护中尤为重要[1]。一直以来,脓毒症、肺炎的临床诊断,细菌性感染以及其他类型疾病的鉴别等,都是临床检验工作的难题[2]。现阶段临床医学关于肺炎与脓毒症的检测主要为C反应蛋白(CRP)、以及PCT(血清降钙素原)两项,然而实际上CRP检测在细菌感染性疾病与非细菌感染性疾病的检测上方便异性较差,因而难以满足临床诊断的需要[3]。故该次研究特选择该院2015年12月—2016年12月期间所收治的57例细菌感染性疾病患者与57例非细菌感染性疾病患者为该次研究对象,并给予其CRP检测及PCT检测,以观察PCT检测在其中的临床价值。以下为该次研究具体报告。……p>
