胡雪梅+陈钊+李华军+徐子莹

[摘要]目的 探讨首发精神分裂症患者行综合护理干预对服药依从性的影响。方法 选取2015年3月～2016年3月我院首发精神分裂患者中抽选76例，按数字法分成对照组和干预组，各38例。对照组给予基础疗法，干预组给予综合护理，比较两组护理效果。结果 干预组服药依从性为94.7%，对照组服药依从性为78.9%，差异有统计学意义（P<0.05）；干预组预后复发4例，占比10.5%；对照组复发12例，占比31.6%，差异有统计学意义（P<0.01）。结论 临床给予首发精神分裂症患者综合护理干预作用显著，可提高服药依从性，加快回归社会速度，值得推广。

[关键词]综合护理干预；首发精神分裂症；服药依从性；生活质量；应用效果

[中图分类号] R749.3 [文献标识码] A [文章编号] 1674-4721（2016）12（a）-0179-03

Effect of comprehensive nursing intervention on medication compliance in first-episode schizophrenic patients

HU Xue-mei CHEN Zhao LI Hua-jun XU Zi-ying

The Second Ward of Male Patients，Psychiatric Hospital of Civil Affairs Bureau in Guangzhou City，Guangzhou 510430，China

[Abstract] Objective To analyze the effect of comprehensive nursing intervention on medication compliance in patients with first-episode schizophrenia.Methods Seventy-six patients with schizophrenia from March 2015 to March 2016 were selected and divided into two groups according to the digital method，with 38 cases in each group.They were performed with different nursing measures as control group （basic therapy） and comprehensive nursing intervention group.The effect was compared.Results The percentage of medication compliance in the intervention group was 94.7%，while in the control group， the rate was 78.9%， which was displayed a statistical difference （P<0.05）.There were 4 cases recurred in the intervention group accounting for 10.5%，while in the control group，12 cases were recurred accounting for 31.6% with a statistical difference （P<0.01）. Conclusion Application of comprehensive nursing intervention in patients with first-episode schizophrenia obtains a significant effect in clinic.It improves the medication compliance and speeds up the return to society，which is worth promoting.

[Key words] Comprehensive nursing intervention；First-episode schizophrenia；Medication compliance；Quality of life； Application effect

精神分裂癥是临床的一种多发性病症，以青壮年为主，病程较为缓慢，以意识、行为、情感障碍为主，严重者可降低生活质量。目前，临床针对该病症均实施抗精神药物疗法，虽可控制病情，但对于改善损伤度、预防复发来说，效果并不理想，因此，临床疾病治疗过程中需加强护理干预，以提高总体效果[1]。

1资料与方法

1.1一般资料

选取2015年3月～2016年3月我院首发精神分裂患者中抽选76例，按随机数字表法分为干预组与对照组，各38例，干预组女性17例，男性21例；年龄20～50岁，平均（39.1±2.6）岁；病史3～30个月，平均（14.1±0.9）个月，对照组女性18例，男性20例；年龄21～50岁，平均（39.2±2.7）岁；病史4～30个月，平均（14.2±0.8）个月。所有患者均经我院医学伦理委员会批准并签署知情同意书。两组患者性别、年龄等一般资料比较，差异无统计学意义（P>0.05），具有可比性。

1.2纳入与排除标准

①纳入标准：患者均符合精神分裂症诊断，接受文化教育时间均在6年以上，身体状况良好，入院时的精神状态评分在30分以上。②排除标准：脏器功能损伤、情感障碍、过度酒精依赖等患者。……