夏琳　张春艳　徐东升

[摘要] 目的 比较Bifluorid 12、脱敏糊剂与传统脱敏剂氟化钠对牙齿洁治术后牙齿过敏症的脱敏效果。 方法 选取2013年6月～2015年6月上海宝山中西医结合医院口腔科门诊洁牙后牙齿过敏症患者82例，239颗患牙，按随机数字表法分成4组进行脱敏治疗，A组20例（62颗牙）使用Bifluorid 12，B组21例（58颗牙）使用脱敏糊剂，C组20例（60颗牙）联合使用Bifluorid 12和脱敏糊剂，D组21例（59颗牙）使用75%的氟化钠，评价四组脱敏剂使用后的即刻脱敏效果、3个月后脱敏效果和6个月后脱敏效果。 结果 A组和C组的即刻脱敏效果均明显高于B组和D组，差异有统计学意义（P < 0.05）。A、B、C组的3个月后脱敏效果均高于D组（P < 0.05）。B组、C组6个月后脱敏效果明显高于A组、D组（P < 0.05）。 结论 各组脱敏剂均有牙本质脱敏的效果，其中即刻效果Bifluorid 12最好，脱敏糊剂能维持较长时间的脱敏效果，氟化钠的脱敏效果无法长期维持。

[关键词] Bifluorid 12；脱敏糊剂；氟化钠；牙齿过敏症

[中图分类号] R78 [文献标识码] A [文章编号] 1673-7210（2017）01（c）-0129-04

[Abstract] Objective To evaluated the effectiveness of Bifluorid 12， herbal desensitizer and sodium fluoride in the treatment of dentin hypersensitivity after periodontal scaling. Methods From June 2013 to June 2015， 239 teeth of 82 patients with dentin hypersensitivity after periodontal scaling of Shanghai Baoshan Hosipital were divided into four groups by random number table. The group A （including 62 teeth of 20 patients） was treated with Bifluorid 12， group B （including 58 teeth of 21 patients） was treated with herbal desensitizer， group C （including 60 teeth of 20 patients） was treated with both Bifluorid 12 and herbal desensitizer and group D （including 59 teeth of 21 patients） was treated with 75% sodium fluoride. The desensitization effects of momentariness， 3 months and 6 months after treatment were examined. Results The immediate effects of group A and group C had the better effectiveness compared to group B and group D （P < 0.05）. 3 month after treatment， there were not statistical difference between group A， group B and group C. However， those all had statistical difference with group D（P < 0.05）. 6 month after treatment， group B and group C showed the better effectiveness， and group A and group D reduced， with statistically significant differences （P < 0.05） Conclusion All desensitizer are effective in treatment of dentin hypersensitivity. Bifluorid 12 has the best immediate effectiveness， herbal desensitizer can maintain a long time effect of desensitization， but the desensitization effect of the sodium fluoride can not.

[Key words] Bifluorid 12； Herbal desensitizer； Sodium fluoride； Dentin hypersensitivity

牙齒对外界的温度、化学刺激敏感，但其本身并无实质性缺损的症状即牙齿过敏症[1-3]。牙齿过敏症发病机制目前尚无定论，最普遍的解释是液体动力学理论[4-5]，临床治疗通过如药物、激光等手段刺激牙神经，产生蛋白变性或形成继发性牙本质，封堵牙本质小管，避免小管内的液体流动，从而达到缓解牙髓不适的效果[6-8]。本研究使用两种脱敏药剂Bifluorid 12和脱敏糊剂，并与传统脱敏剂氟化钠作对比，对药物的即刻效果和远期效果进行临床评估。

1 材料与方法

1.1 一般资料

选择2013年6月～2015年6月到上海宝山中西医结合医院（以下简称“我院”）口腔科主述有洗牙后牙本质过敏症状的82例患者。年龄30～60岁，平均年龄（41.42±2.26）岁。其中男38例，女44例，病牙共计239颗。同时排除以下情况：①有全冠修复者；②有牙髓炎症状者；③近期3个月内进行过脱敏治疗者；……