林超

摘要：目的分析观察紫草汤联合西药治疗湿热瘀阻型多囊卵巢综合征的临床疗效。方法选取于本院诊治的湿热瘀阻型多囊卵巢综合征的患者60例，采用随机数字表法分为观察组和对照组，对照组30例患者给予常规西药治疗，观察组30例患者给予常规西药联合紫草汤治疗。分析比较2组患者的临床疗效、不良反应发生率和治疗前后的卵泡雌激素（FSH）、黄体生成素（LH）水平、睾酮（T）、黄体生成素与卵泡雌激素的比值（LH/FSH）变化。结果治疗前，2组患者的FSH、T、LH、LH/FSH比较无统计学意义（P>005）；治疗后，2组患者的FSH较治疗前无明显变化，比较无统计学意义（P>005）；T、LH、LH/FSH显著降低，观察组患者的T、LH、LH/FSH水平低于对照组，差异有统计学意义（P<005）；观察组患者的临床疗效优于对照组患者，差异有统计学意义（P<005）；观察组患者的不良反应发生率低于对照组患者，差异有统计学意义（P<005）。结论紫草汤联合西药治疗湿热瘀阻型多囊卵巢综合征疗效显著，安全性高，值得临床推广使用。

关键词：紫草汤；多囊卵巢综合征；湿热瘀阻型；临床疗效

中图分类号：R2711文献标志码：B文章编号：1007-2349（2016）09-0039-03

【Abstract】Objective： To analyze of clinical effect of Lithospermum Decoction combined with western medicine on the treatment of polycystic ovary syndrome patients with dampness and hotness obstruction. Methods： 60 patients were selected and randomly divided into an observation group and a control group， 30 cases per group. The control group was treated with conventional western medicine while the observation group was treated with conventional medicine combined with Lithospermum Decoction. The clinical effect and the incidence of adverse reactions of the two groups and their FSH， luteinizing hormone （LH）， testosterone （T）， and the changes of luteinizing hormone and follicle estrogen （LH/FSH） ratio were compared before and after the treatment. Results： Before the treatment， the comparison of FSH， T， LH， LH / FSH of the two groups showed no statistical significance （P>005）. After the treatment， the comparison of FSH of the two groups had no significant change compared with the pre-treatment， no statistically significant （P>005）， but their T， LH， LH/FSH significantly decreased. The level of T， LH， LH /FSH of the observation group was lower than that of the control group， and the difference was statistically significant （P< 005）. The clinical effect of the observation group was better than that of the control group and the difference was statistically significant （P<005）. The incidence of adverse reactions of the observation group was lower than that of the control group and the difference was statistically significant （P<005）. Conclusion： Lithospermum Decoction combined with western medicine has obvious effect on the treatment of polycystic ovary syndrome with dampness and hotness obstruction， safe and worthy of more clinical application.

【Key words】Lithospermum Decoction， polycystic ovary syndrome， dampness and hotness obstruction， clinical effect

多囊卵巢综合征是临床常见的妇科内分泌综合征，临床症状多表现为月经失调、痤疮、肥胖、不孕，严重者可导致子宫内膜癌、血脂异常、心血管疾病等[1]。对于多囊卵巢综合征，现代中医学者辨证论治取得了良好的临床效果，表明中医治疗多囊卵巢综合征的巨大潜力[2]，本文分析观察对多囊卵巢综合征使用紫草汤联合西药治疗的临床效果。现报道如下。

1资料与方法

11一般资料选取2013年9月—2015年8月于本院诊治的多囊卵巢综合征患者60例，随机分为观察组和对照组。观察组患者年龄18～38岁，平均年龄（2535±264）岁；病程1～9 a，平均病程（586±153）a。对照组患者年龄20～37岁，平均年龄（2497±152）岁；病程2～9 a，平均病程（608±057）a。比较2组患者年龄、病程无统计学意义（P>005），有可比性。西医……