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托吡酯与卡马西平联合治疗脑梗死后继发癫痫疗效对比分析

2016-07-25殷鹏

中国卫生标准管理 2016年5期

殷 鹏



托吡酯与卡马西平联合治疗脑梗死后继发癫痫疗效对比分析

殷 鹏

【摘要】目的 分析脑梗死后继发癫痫患者实施托吡酯与卡马西平治疗的疗效。方法 2013年11月~2015年12月我院将94例脑梗死后继发癫痫患者通过电脑随机分组的方式,分为治疗组和常规组,每组患者均为47例。常规组采用卡马西平治疗,而治疗组给予托吡酯治疗。对比分析两组患者的治疗效果。结果 采取不同方式后,治疗组患者总有效率为91.49%(43/47);常规组患者总有效率为76.60%(36/47)。治疗组优于常规组(P<0.05)差异具有统计学意义。结论 针对于脑梗死后继发癫痫患者来讲,在对其进行治疗的过程中,运用托吡酯效果优于卡马西平,可对患者的症状起到良好的改善作用。

【关键词】脑梗死后继发癫痫;托吡酯;卡马西平;效果分析

Objective To analyze the effect of topiramate and carbamazepine in patients with secondary epilepsy after cerebral infarction. Methods From November 2013 to December 2015,94 patients with secondary epilepsy after cerebral infarction were randomly divided into treatment group and control group,47 cases in each group. The conventional group received the carbamazepine treatment,while the treatment group received topiramate treatment. The therapeutic effect of the two groups were compared and analyzed. Results In different ways,the total effective rate was 91.49%(43/47)in the treatment group,and the total effective rate was 76.60%(36/47)in the conventional group. The treatment group was significantly better than the conventional group(P<0.05),the difference was significant. Conclusion In terms of epilepsy secondary to cerebral infarction patients,in the treatment process,using topiramate effect is better than that of carbamazepine,a good effect on the patient's symptoms,clinical worth promoting the use.

【Key words】 Epilepsy secondary to cerebral infarction,Topiramate,carbamazepine,Effect analysis

继发性癫痫是脑梗死患者的常见并发症,当患者发生继发性癫痫后可使患者的脑部组织出现进一步受损,严重影响患者的神经功能恢复[1],同时也将对患者的预后产生不利影响。为改善患者的预后,需对脑梗死后继发癫痫患者采取积极有效的治疗措施,从而保证治疗效果。此次研究将分析脑梗死后继发癫痫患者实施托吡酯与卡马西平治疗的疗效。现报道如下。

1 一般资料与方法

1.1 一般资料

2013年11月~2015年12月我院将94例脑梗死后继发癫痫患者通过电脑随机分组的方式,分为治疗组和常规组,每组患者均为47例。常规组采用卡马西平治疗,而治疗组给予托吡酯治疗。治疗组中29例男性患者,18例女性患者,年龄47~75岁,平均(56.3±10.1)岁;……

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