夏建珍

摘 要 目的：评价疏风解毒胶囊联合复方氨酚烷胺胶囊治疗大学生流感样疾病的临床疗效和安全性。方法：选取大学生流感样病例患者300例，随机分为疏风解毒胶囊联合复方氨酚烷胺胶囊治疗组（治疗组）和单用复方氨酚烷胺胶囊治疗组（对照组）。治疗组口服复方氨酚烷胺胶囊1粒，每天2次，加用疏风解毒胶囊口服4粒，每天3次；对照组口服复方氨酚烷胺胶囊1粒，每天2次。观察两组治疗后3 d的体温、咽痛/咳嗽症状，评价疗效及安全性。结果：治疗组总有效率为94.2%，对照组为87.5%，组间差异有统计学意义（P<0.05）。结论：疏风解毒胶囊联合复方氨酚烷胺胶囊治疗大学生流感样病例疗效显著，能有效缓解患者症状，促进康复。

关键词 流感 疏风解毒胶囊 疗效评价

中图分类号：R511.7 文献标志码：A 文章编号：1006-1533（2016）12-0037-03

Effect of shufengjiedu capsule combined with compound paracetamol and amantadine hydrochloride capsule in the treatment of influenza-like illness in the university students

XIA Jianzhen

（Hospital of Central University for Nationalities， Beijing 100081， China）

ABSTRACT Objective： To evaluate the clinical efficacy and safety of shufengjiedu capsule combined with compound paracetamol and amantadine hydrochloride capsule in the treatment of influenza-like illness in the university students. Methods： Three hundred university students with influenza-like illness were selected and randomly divided into a treatment group of shufengjiedu capsule combined with compound paracetamol and amantadine hydrochloride capsule and a control group of compound paracetamol and amantadine hydrochloride capsule only. The treatment group was received one capsule of compound paracetamol and amantadine hydrochloride capsule， twice daily， meanwhile， added with 4 capsules of shufengjiedu capsule， thrice daily. The control group was received one capsule of compound paracetamol and amantadine hydrochloride capsule， twice daily. The symptoms of temperature and sore throat/cough， the treatment efficacy and safety were observed in the two groups after three days treatment. Results： The total effective rate was 94.2% and 87.5% in the treatment and the control groups， respectively. The difference between the two groups had the statistical significance（P<0.05）. Conclusion： Shufengjiedu capsule combined with compound paracetamol and amantadine hydrochloride capsule in the treatment of influenza-like illness in the university students has significant effect which can effectively alleviate the symptoms of patients and promotes the rehabilitation.

KEY WORDS influenza； shufengjiedu capsule； evaluation of treatment effect

流感是一种严重危害人类健康的急性呼吸道传染病，潜伏期短，经飞沫传播，变异快，人群对变异株普遍易感，控制难度大。研究发现，医疗机构流感样疾病（influenza-like illness，ILI）占门、急诊病例总数百分率与流感病毒阳性率呈正相关，表明医疗机构监测到的ILI流行规律与流感病毒流行规律具有较高的一致性，通过ILI的初期筛查，可为流感的早期诊断提供帮助[1-2]。高校大学生暴露在人员密集场所，容易受流感病毒侵犯，因此积极检测并治疗ILI十分重要。但作为基层医院，很难有条件对每例发热患者进行病原学检查，对于ILI的确诊比较困难。由于ILI病原体比较复杂，治疗尚无覆盖所有病原体的有效药物，临床上多采用以抗病毒为主的对症治疗[3]。本文旨在探讨疏风解毒胶囊联合复方氨酚烷氨胶囊在治疗ILI中的临床疗效。……