李文东



奥曲肽治疗肝硬化上消化道出血的临床分析

李文东

【摘要】目的 探究肝硬化上消化道出血患者采用奥曲肽治疗的方法和效果。方法 选取2014年10月～2015年10月收治的79例肝硬化上消化道出血患者进行治疗，随机分组，实验组41例患者采取奥曲肽的治疗，对照组38例患者接受常规药物的治疗，比较患者的治疗效果。结果 实验组患者治疗有效率为92．68%，对照组治疗有效率为81．58%。实验组患者的治疗效果高于对照组，差异有统计学意义（P＜0．05）。结论 肝硬化上消化道出血患者采用奥曲肽治疗，可以改善身体情况，疗效显著，不良反应较少。

【关键词】肝硬化上消化道出血；奥曲肽；治疗方法

Objective Octreotide treatment method and its effect for liver cirrhosis complicated with upper digestive tract hemorrhage are to be studied．Methods Chose 79 patients of liver cirrhosis complicated with upper digestive tract hemorrhage who were treated in hospital from October 2014 to October 2015 and separated them into two groups at random，41 patients in study group were given octreotide treatment，while another 38 patients in control group were given conventional medication treatment and then compared treatment effects between two groups． Results Patients’ nursing efficacy in study group was 92．68%，which was much higher than 81．58% in control group． Thus，nursing efficacy was much better in study group compared to that in control group，there was a differential between two groups and such a differential had statistic value（P＜0．05）． Conclusion Octreotide treatment is effective for liver cirrhosis complicated with upper digestive tract hemorrhage，it is conducive to improving patients’ physical condition with few side effects．

【Key words】 Liver cirrhosis complicated with upper digestive tract hemorrhage，Octreotide，Treatment method

肝硬化患者会增高门静脉压力，导致食管胃底静脉曲张而破裂出血，上消化道大出血为常见的并发症，一旦破裂，会对患者生命造成严重威胁，很多肝硬化患者都因为这一原因死亡［1］。目前多选择缩血管药物，包括生长抑素和血管加压素。一定要及时采取有效的治疗药物，奥曲肽这一药物疗效显著，且安全性高，很少有患者出现不良反应［2］。本次研究选取2014年10月～2015 年10月收治的79例肝硬化上消化道出血患者进行治疗，观察患者的治疗效果，现报告如下。

1 资料和方法

1.1 一般资料

本次研究选取2014年10月～2015年10月收治的79例肝硬化上消化道出血患者进行治疗，实验组患者41例，男性24例，女性17例，年龄37～72岁，平均年龄（46.35±6.92）岁，18例为少量出血，17例为中等量出血，6例为大量出血。对照组患者38例，男性22例，女性16例，年龄34～73岁，平均年龄（47.02±6.12）岁，23例为少量出血，11例为中等量出血，4例为大量出血。……