加味没竭片治疗子宫内膜异位痛经

詹瑾，王婷婷，指导：须义贞*，赵莉

(上海中医药大学附属岳阳中西医结合医院，上海 200437)

摘要：目的观察加味没竭片治疗子宫内膜异位症痛经的临床疗效。方法将120例患者随机分成2组,治疗组60例服用加味没竭片，对照组60例服用血府逐瘀胶囊，2组均治疗3个月为1个疗程。结果治疗组痛经情况评分总有效率90%,治疗后患者痛经程度较治疗前降低(P<0.05);中医证候评分总有效率90%。对照组痛经情况评分总有效率86.67%，治疗后患者痛经程度较治疗前降低(P<0.05)；中医证候评分总有效率93.33%。治疗组与对照组对痛经程度的总有效率无统计学意义(P>0.05)。治疗组与对照组中医证候疗效无差别(P>0.05)。2组治疗前后CA125变化均有统计学意义。结论加味没竭片能改善子宫内膜异位症患者的痛经程度，与血府逐瘀胶囊对子宫内膜异位症患者痛经程度、中医证候疗效的总有效率均无统计学意义。

关键词：痛经;子宫内膜异位症/中医药疗法;加味没竭片/临床应用

DOI:10.13463/j.cnki.jlzyy.2015.04.022

中图分类号：R271.11文献标志码： A

文章编号：1003-5699(2015)04-0384-03

基金项目:上海市卫生局：加味没竭片治疗子宫内膜异位症痛经的规范化研究(2011ZJ017);上海市中医药事业发展三年行动计划“海派中医朱氏妇科传承研究基地项目”(ZYSNXD-CC-HPGC-JD-008)；国家中医药管理局重点专科妇科(ZK0901FK012)。

作者简介:詹瑾(1989-)，女，硕士研究生，主要从事中西医结合妇科内分泌疾病的研究。

收稿日期:(责任编辑：王丹2014-09-16)

*通信作者:须义贞,电话-18930562661,电子邮箱-13162287959@163.com

JiaweiMojie tablet in treatment of dysmenorrhea caused by endometriosis

ZHAN Jin,WANG Tingting,Instructor:XU Yizhen*,ZHAO Li

(Yueyang Combine Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai

University of Traditional Chinese Medicine,Shanghai 200437,China)

Abstract:ObjectiveTo observe the clinical efficacy of JiaweiMojie tablet in treatment of dysmenorrhea caused by endometriosis.MethodsThe 120 cases were divided into 2 groups randomly.60 in the treatment group take JiaweiMojie tablet while the other 60 in the control group take Xuefuzhuyu capsule.Both groups have been treated for three months.ResultsThe total effective rate of dysmenorrhea scale score of treatment group is 90%.The dysmenorrhea scale after treatment is lower than before in treatment group (P<0.05).The total effective rate of TCM syndrome score of treatment group is 90%.The total effective rate of dysmenorrhea scale score of control group is 86.67%.The dysmenorrhea scale after treatment is lower than before in control group (P<0.05).The total effective rate of TCM syndrome score of control group is 93.33%.There is no statistic difference between the treatment group and the control group in dysmenorrhea scale (P>0.05).There is no statistic difference between the treatment group and the control group in TCM syndrome score (P>0.05).The variation of CA125 before and after treatment has statistic difference in both groups.ConclusionJiaweiMojie tablet can relieve the dysmenorrhea scale of patients with endometriosis.There is no statistic difference in the total effective rate of dysmenorrhea scale and TCM syndrome between JiaweiMojie tablet and Xuefuzhuyu capsule.

Keywords:dysmenorrheal;endometriosis;Jiawei Mojie tablet;clinical application

子宫内膜异位症是育龄期妇女的多发病，发病率有明显的上升趋势，是妇科的常见病、多发病、难治病。目前西医治疗本病多采用激素及手术疗法，但因其复发率高，不良反应多，易远处转移及种植而被部分患者所不能接受。加味……