抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿的临床效果分析
2015-10-21汤继跃
汤继跃
【摘要】目的:分析抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿的临床效果。方法:回顾性分析66例老年慢性阻塞性肺气肿患者的临床资料,将其随机分为观察组与对照组,每组各33例,所有患者均进行基础治疗,其中对照组采用抗生素治疗,观察组采用抗生素联合糖皮质激素的治疗方案,比较两组的血气指标改善情况及治疗效果。结果:经过治疗所有患者的氧分压及二氧化碳分压均有显著改善,而观察组指标改善效果优于对照组,差异具统计学意义(P<0.05);观察组总有效率90.91%,对照组总有效率75.76%,观察组显著高于对照组,差异具统计学意义(P<0.05)。结论:抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿效果确切,值得临床推广。
【关键词】抗生素;糖皮质激素;老年慢性阻塞性肺气肿
【Abstract】 Objective: to analyze the clinical effects of antibiotics combined with glucocorticoid in the treatment of elderly patients with chronic obstructive pulmonary emphysema. Methods: retrospective analysis of the clinical data of 66 cases of elderly patients with chronic obstructive pulmonary emphysema, it will be randomly divided into observation group and control group, 33 cases in each group, all the patients were given the basic treatment, the control group used antibiotic treatment, the observation group used antibiotic therapy combined with glucocorticoids, blood gas indexes comparison of two group improved conditions and treatment effect. Results: after treatment, all patients with partial pressure of oxygen and carbon dioxide partial pressure were significantly improved, and the observation group index is significantly better than that of control group, the difference has statistical significance (P<0.05); observation group total effectiveness 90.91%, the comparison group total effectiveness 75.76%, the observation group was significantly higher than that of the control group, the difference has statistical significance (P<0.05). Conclusion: antibiotics combined with glucocorticoid an exact treatment of senile chronic obstructive emphysema, is worth the clinical promotion.
【key words 】antibiotics; glucocorticoid; elderly patients with chronic obstructive pulmonary emphysema
【中图分类号】R722.12 【文献标识码】B【文章编號】1004-4949(2015)03-0135-01
慢性阻塞性肺气肿(COPD)是指职业性粉尘、有害气体、气候、吸烟等相关因素导致的慢性肺部疾病,如不及时治疗会导致肺部癌变,对患者的身心健康产生严重影响[1]。临床上多采用肺减容术进行治疗,但是老年患者往往对手术不耐受,所以多采用保守治疗。本研究以66例老年慢性阻塞性肺气肿患者为研究对象,分析抗生素联合糖皮质激素的治疗效果。现报道如下。
1 资料与方法
1.1 临床资料
回顾性分析我院2014年1月至2014年12月收治的66例老年慢性阻塞性肺气肿患者的临床资料,其中男37例,女29例,年龄61-77岁,平均年龄67.3岁;病程2-11年,平均5.4年。将66例患者随机分为观察组与对照组,每组各33例,两组患者的一般资料差异不具统计学意义(P>0.05),具有可比性。
1.2 方法
所有患者入院后均进行常规基础治疗,包括平喘、化痰、解痉、吸氧等;对……
