郭颖

[摘要] 目的 探究嗜酸性细胞增多性皮炎患者的临床特点。方法 随机选取该院收治的70例嗜酸性细胞增多增多综合征作为研究对象，将其纳入该研究的观察组；另外35例健康体检者作为对照组，对两组入选病例的临床资料、实验室检查结果及临床表现进行统计分析，做好相关记录。结果 比较两组性别、年龄差异无统计学意义（P>0.05）；观察组皮肤损害系数、低蛋白血症、血沉增快、肝脏增大、脾脏增大发生率高于对照组，外周血白细胞的数量多于对照组（P<0.05）。观察组患者经临床治疗后，均康复出院。结论 嗜酸性细胞增多性皮炎好发于老年男性患者，患者的首发症状均为瘙痒性皮炎，随着病情进展，患者可见红色斑点、疱疹、出血、结痂等症状。尽早分析嗜酸性细胞产生的外部及内部因素，对于遏制病情及制定有针对性的方法具有重要的意义。

[关键词] 嗜酸性细胞增多性皮炎；患者；临床研究

[中图分类号] R758 [文献标识码] A [文章编号] 1674-0742（2015）04（c）-0026-02

[Abstract] Objective To explore the 70 cases of eosinophilia of the clinical features of patients with dermatitis. Methods Selected an increase of 70 cases in our hospital hypereosinophilic syndrome as research subjects， and included in the present study observation group； another 35 healthy subjects as the control group， two groups of selected cases of clinical data， laboratory test results and clinical manifestations of statistical analysis， make relevant records. Results Compared the gender， age of the two groups， the differences were not statistically significant（P> 0.05）； skin damage factor， hypoalbuminemia， ESR， increased liver， spleen increased incidence of the observation group was higher than that of the control group， the number of peripheral blood leukocytes was more than that of the control group（P<0.05）. The clinical observation of patients after treatment， were discharged. Conclusion Hypereosinophilic dermatitis occurs in older male patients， the first symptom of the patient are itching dermatitis， as the disease progresses， patients can see red spots， sores， bleeding， crusting and other symptoms. Early analysis of external and internal factors produced by eosinophils， for curbing the disease and to develop targeted approach has important significance.

[Key words] Hypereosinophilic dermatitis； Patients； Clinical study

嗜酸性细胞增多性皮炎是由不同的异质性细胞增多产生的一种疾病，嗜酸性细胞增多性皮炎在诊断的时候不容易发现病因，会因为不能正确地分析出发病机制，导致误诊的问题[1]。为探究嗜酸性细胞增多性皮炎患者的临床特点，该院把收治的70例患有嗜酸性细胞增多性皮炎的病人进行探究，现报道如下。

1 资料与方法

1.1 一般资料

随机选取在该院治疗的70例患有嗜酸性细胞增多性皮炎患者，将其纳入该研究的观察组；另外35例健康体检者作为对照组，观察组患者均符合嗜酸性粒细胞增多诊断的诊断标准：骨髓中嗜酸性粒细胞增多、皮肤与内脏受累证据，临床表现为皮肤症；外周血嗜酸性粒细胞明显增加，绝对计数超过1500×10/L，持续时间超过6个月；除外嗜酸性粒细胞增多的其他疾病；患者体内的器官受到不良的影响。