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云南省接受HAART治疗的老年艾滋病患者中医体质研究

2021-10-14杨玉琪孙俊瞿广城陆中云蒲亚萍和丽生

云南中医中药杂志 2021年9期
关键词:老年

杨玉琪 孙俊 瞿广城 陆中云 蒲亚萍 和丽生

摘要:目的 调查云南省接受HAART治疗的老年艾滋病患者的中医体质分布情况,为老年艾滋病中西医结合治疗提供参考。方法 采用王琦教授编制的“中医体质量表”,对接受HAART治疗满1年的729例老年艾滋病患者(≥50岁)进行中医体质判定,并对中医体质类型分布进行分析。结果 729例老年艾滋病患者中,平和质503例(69.00%),偏颇体质226例(31.00%),偏颇体质中频数由高到低依次为阳虚质、气虚质、气郁质、阴虚质、痰湿质、湿热质、血瘀质及特禀质;单因素分析患者性别、职业、可能感染途径对体质影响显著(P<0.05),民族、年龄、婚姻状况、文化程度、HAART治疗时长等对体质影响不明显(P>0.05);平和质、阳虚质、气虚质3种主要体质类型的老年艾滋病患者HAART治療后CD4+T淋巴细胞计数较治疗前均显著增加(P<0.01),治疗前后组间比较差异无统计学意义(P>0.05)。结论 云南省接受HAART治疗的老年艾滋病患者中医体质以平和质为主,患者性别、职业、可能感染途径对中医体质类型有明显影响,平和质、阳虚质、气虚质 3种主要体质类型的老年艾滋病患者HAART治疗后CD4+T淋巴细胞计数较治疗前均显著增加。

关键词:艾滋病;老年;中医体质;云南

中图分类号:R512.91   文献标志码:B   文章编号:1007-2349(2021)09-0025-04

A Study in Yunnan: How HAART Approach Affect Traditional Chinese MedicineConstitution of the Aged AIDS Patients

YANG Yu-qi, SUN Jun, QU Guang-cheng, LU Zhong-yun, PU Ya-ping, HE Li-sheng

(Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming 650223, China)

【Abstract】Objective: To investigate traditional Chinese medicine constitution (TCMC) classification among elderly AIDS patients receiving HAART treatment in Yunnan Province, so as to provide evidence for integrating TCM with Western medicine in treating the elderly AIDS patients. Methods: According to "TCMC Table" compiled by Professor Wang Qi, 729 elderly AIDS patients (≥50 years old) who had received HAART treatment for one year were evaluated and analyzed. Results: Among the 729 elderly AIDS patients, 503 (69.00%) were normal constitution and 226 cases were lopsided constitution (31.00%). The frequency of lopsided constitution from high to low was Yang-deficiency, Qi-deficiency, Qi-stagnation, Yin-deficiency, phlegm-dampness diathesis, damp-heat, blood-stasis and special diathesis. The univariate analysis showed that patients' gender, occupation, possible infection routes had significant effects on TCMC (P<0.05), however, ethnicity, age, marital status, education level, HAART treatment duration, etc. had no significant effect on TCMC (P>0.05). In addition, the CD4+T lymphocyte counts of elderly AIDS patients significantly increased after HAART treatment (P<0.01) in three types of TCMC (normal constitution, Yang-deficiency constitution and Qi-deficiency constitution), nevertheless, there was no statistically significant difference within these three groups (P<0.05). Conclusion: The TCMC of the elderly AIDS patients receiving HAART treatment in Yunnan Province is mainly composed of normal constitution. gender, occupation and potential infection routes have a significant impact on TCMC. The CD4+T lymphocyte counts of elderly AIDS patients after HAART treatment significantly increase mainly in three types of constitution: normal, Yang deficiency, and Qi deficiency.

【Key words】AIDS; Elderly; Traditional Chinese Medicine Constitution; Yunnan

艾滋病(acquired immunodeficiency syndrome,AIDS)在我国流行已有30多年,其感染人群主要集中在青壮年,但近年来老年人感染人类免疫缺陷病毒(Human Immunodeficiency Virus,HIV)的比例有增加的趋势[1]。老年艾滋病患者在人口学、疾病特征及治疗影响因素方面有别于青壮年,在治疗过程中需针对性的采取治疗措施才取得较好的临床疗效[2,3]。王琦教授提出的中医体质学说主张辨体论治,体质是个体相对稳定的生理特性,不同的体质是产生疾病差异的内在基础,因而体质分类研究也是从深层次认识疾病和提供个性化诊疗的前提[4,5]。……

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