陈金中 伍玉军 岑迎贺 郑涛 吴志明

摘要：目的：探讨鼻内镜下高选择性翼管神经分支及筛前神经切断治疗变应性鼻炎;方法：将医院2017年3月至2019年2月收治的80变应性鼻炎患者作为治疗观察对象，根据患者选择的治疗方式进行分组，即对照组和治疗组，两组均为40例，其中，对照组患者给予鼻内糖皮质激素及口服抗组胺药物治疗，而治疗组采取鼻内镜下高选择性切断翼管神经分支及筛前神经治疗，治疗一段时间后比较两组患者的临床治疗效果。结果：两组治疗后3个月、6个月有效率比较，治疗组均高于对照组（P<0.05）。比较治疗组治疗前后评分，治疗后高于治疗前，组内差异显著（P<0.05）结论：对变应性鼻炎患者采用鼻内镜下高选择性切断翼管神经分支及筛前神经治疗方式，相比于采用保守药物治疗，取得的临床效果更加明显，可有效改善患者病情，提升恢复效果，具有更高的社会效益与经济效益，值得推广使用。

关键词：鼻内镜下;高选择性;翼管神经分支;筛前神经;变应性鼻炎

【中图分类号】R322.8 【文献标识码】A 【文章编号】2107-2306（2020）01-024-02

[Abstract] Objective： To explore the treatment of allergic rhinitis by high selectivity pterygoid nerve branch and anterior ethmoidal nerve transection under nasal endoscopy. Methods： 80 patients with allergic rhinitis admitted to our hospital from March 2017 to February 2019 were divided into two groups according to the treatment methods chosen by the patients： the control group and the treatment group， 40 cases in each group. Glucocorticoids and oral antihistamines were administered in the treatment group， while high selective transection of pterygoid nerve branches and anterior ethmoidal nerve under nasal endoscope was used in the treatment group. The clinical effects of the two groups were compared after a period of treatment. Result： The effective rate of the two groups was higher than that of the control group at 3 months and 6 months after treatment （P < 0.05）. The scores before and after treatment in the treatment group were significantly higher than those before treatment （P < 0.05）.Conclusion： The treatment of allergic rhinitis with highly selective transection of pterygoid nerve branch and anterior ethmoidal nerve under nasal endoscope is more obvious than that of conservative drug therapy， which can effectively improve the condition of patients and improve the recovery effect. It has higher social and economic benefits and is worth popularizing and using.

[Key words] Nasal endoscopy; high selectivity; pterygoid nerve branch; anterior ethmoidal nerve; allergic rhinitis

變应性鼻炎属于IgE介导的鼻粘膜非感染性疾病，该病患者鼻黏膜神经功能表现异常，鼻腔黏膜血管扩张，腺体分泌增加，常见鼻塞和清水样涕症状，临床治疗难度较大[1]。且受环境影响较为严重，随着病情严重程度不断提升，会对患者的日常生活、学习和工作等产生严重影响。相关研究表明，变应性鼻炎主要疾病机制为神经机制和免疫机制，并在此基础上展开相应治疗[2]。……