毛一清　魏云海　朱云

[摘要] 目的 分析胃癌全胃切除術后早期肠内营养支持的临床效果。 方法 选取2017年9月至2019年7月我院收治的胃癌全胃切除术患者68例，随机分为研究组和对照组，每组各34例。对照组采用完全肠外营养支持，研究组采用早期肠内营养支持，观察比较两组患者的临床效果、肛门排气时间、排便时间以及住院时间;并比较两组治疗过程中发生的不良反应。 结果 研究组患者总有效率为91.18%，明显高于对照组的73.53%，差异有统计学意义（P<0.05）;研究组患者肛门排气时间、排便时间及住院时间均明显短于对照组，差异有统计学意义（P<0.05）;研究组患者不良反应总发生率为5.88%，明显低于对照组的17.65%，差异有统计学意义（P<0.05）。 结论 胃癌全胃切除术患者经早期肠内营养支持效果理想，能缩短住院时间，降低不良反应发生的可能性，可有效增强治疗效果，临床上应进一步推广使用。

[关键词] 胃癌;全胃切除术;早期;肠内营养支持

[中图分类号] R735.2          [文献标识码] A          [文章编号] 1673-9701（2021）06-0017-03

The clinical effect of enteral nutrition support in the early stage after total gastrectomy for gastric cancer

MAO Yiqing1   WEI Yunhai2   ZHU Yun3

Department of Gastrointestinal Surgery， Huzhou Central Hospital in Zhejiang Province， Affiliated Center Hospital of Huzhou Teachers College， Huzhou   313000， China

[Abstract] Objective To analyze the clinical effect of enteral nutrition（EN） support in the early stage after total gastrectomy for gastric cancer（GC）. Methods A total of 68 patients admitted to and treated in our hospital from September 2017 to July 2019 that underwent total gastrectomy for GC were selected and randomly divided into the study group and the control group，with 34 patients in each group. The control group was received total parenteral nutrition support，while the study group was received EN support in the early stage. The clinical effect， the anal exhaust time， the defecation time and the hospitalization time between the two groups were observed and compared. The adverse reactions（ADRs） that occurred during the treatment between the two groups were also observed and compared. Results The total effective rate in the study group was 91.18%， which was significantly higher than that of 73.53% in the control group， with significant difference（P<0.05）. The anal exhaust time， the defecation time and the hospitalization time in the study group were respectively significantly shorter than those in the control group， with significant difference（P<0.05）. The total incidence of ADRs in the study group was 5.88%， which was significantly lower than that of 17.65% in the control group， with significant difference（P<0.05）. Conclusion EN support in the early stage produces an ideal effect on the patients who have undergone total gastrectomy for GC. It can shorten the hospitalization time， lower the incidence of ADRs， and enhance the curative effect effectively. It should be further promoted and applied in clinical practice.

[Key words] Gastric cancer; Total gastrectomy; The early stage; Enteral nutrition support

胃癌属于消化道内常见恶性肿瘤之一。随着生活水平的不断提升，人们的生活方式及饮食习惯等发生了明显的变化，同时胃癌的发生率也随之升高，严重影响了人们的日常生活和工作[1]。临床上多应用全胃切除术对晚期胃癌患者实施治疗，但手术结束后，大多数患者会出现不同程度的营养不良症状，且患者在接受全胃切除术前需要进行较长时间的禁食。因此，必要的营养支持是促进患者早日恢复的重要方式。但长时间对患者实施肠外营养支持会导致其出现肠道黏膜萎缩及肠道功能紊乱等并发症，因此早期肠内营养比较适合肠道的正常生理过程，可有效促进肠道功能的恢复[2-3]。本研究分析胃癌全胃切除术后应用早期肠内营养支持的临床效果，现报道如下。

1 资料与方法

1.1 一般资料

选取2017年9月至2019年7月我院收治的胃癌全胃切除术患者68例，随机分为研究组和对照组，每组各34例。……