降阶梯抗生素方案治疗老年重症肺炎的临床分析
2020-11-10张金英
张金英


[摘要] 目的 分析降阶梯抗生素药物治疗方案实施在老年重症肺炎患者临床治疗过程中的意义。方法 方便选取2018年3月—2019年11月该医院治疗的62例老年重症肺炎患者实施数据指标项目研究,选择随机双盲方式开展分组研究,每组31例,实验组采用降阶梯抗生素药物治疗方案,参比组采用传统抗生素药物治疗方案,总结抗生素药物治疗有效统计数、咳嗽消除所用时长、啰音消除所用时长。结果 实验组抗生素药物治疗有效统计数(96.77%)对比参比组(77.42%)增加(χ2=5.166,P=0.023<0.05);实验组咳嗽消除所用时长、啰音消除所用时长[(11.56±2.50)d、(10.20±1.35)d]对比参比组[(15.40±3.12)d、(14.69±2.30)d]减少(t=5.347、9.373,P=0.000、0.000<0.05)。结论 为老年重症肺炎患者选用降阶梯抗生素药物治疗方案表现出较好用药效果。
[关键词] 降阶梯抗生素方案;老年;重症肺炎
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2020)08(c)-0023-03
[Abstract] Objective To analyze the significance of de-escalation antibiotic therapy in the clinical treatment of elderly patients with severe pneumonia. Methods A data index project study was carried out on 62 elderly patients with severe pneumonia treated convenient selection in the hospital from March 2018 to November 2019. Random double-blind group research was carried out on the above cases, and 31 cases in each group. The experiment group was treated with de-escalation antibiotics, and the reference group was treated with traditional antibiotics. The effective statistics of antibiotic treatment, the time taken to eliminate cough, and the time taken to eliminate rales were summarized. Results The effective statistics of antibiotic treatment in the experimental group (96.77%) increased compared with in the reference group(77.42%) (χ2=5.166, P=0.023<0.05); the time used to eliminate cough and rale in the experimental group [(11.56±2.50)d, (10.20±1.35)d]; the comparison reference group [(15.40±3.12)d, (14.69±2.30)d] decreased (t=5.347, 9.373, P=0.000, 0.000<0.05). Conclusion The selection of de-escalation antibiotics for elderly patients with severe pneumonia shows a good drug effect.
[Key words] De-escalation antibiotic regimen; Elderly; Severe pneumonia
重症肺炎为病原微生物导致的肺泡以及气道严重炎症疾病,多将该病患者收入医院重症监护室[1]。重症肺炎患者多存在胸部疼痛、情况咳嗽发生、发热现象等,重症肺炎患者病情改变速率相对较快,具有比较多的并发症情况,对重症肺炎患者生命安全形成一定威胁性[2]。老年重症肺炎患者常同时存在多种疾病,机体免疫能力降低,加大病死率[3]。临床上常为老年重症肺炎患者选择抗生素药物治疗方法,不过,传统抗生素药物对症治疗很难将老年重症肺炎患者病情予以積极控制,难以得到较佳抗生素药物治疗效果[4]。降阶梯抗生素药物治疗方案依据细菌流行病学说、老年重症肺炎患者感染严重性及其症状表现予以对应治疗,可提升抗生素药物治疗有效性[5]。该文针对2018年3月—2019年11月该医院治疗的62例老年重症肺炎患者予以指标详细分析,探究降阶梯抗生素药物治疗方案开展于老年重症肺炎患者临床治疗过程中的价值,现报道如下。……
