聚乙二醇在结肠镜检术前不同时间给药对患者睡眠情况和肠道清洁度影响分析
2020-10-21吴丽姗
吴丽姗



摘要 目的:探究聚乙二醇在結肠镜检术前不同时间给药对患者睡眠情况及肠道清洁度的影响。方法:选取2018年6月至2019年3月在福建泉州市第一医院住院并接受结肠镜检术患者93例作为研究对象,随机分为A、B、C3组,每组31例。A组患者术前1 d 16:00及手术当天10:00各大给药1次;B组患者术前1 d 19:00及手术当天10:00各给药1次,C组患者手术当天6:00-11:00给药2次,比较分析3组给药后其肠道清洁度、术前1 d晚睡眠质量并不良反应发生率。结果:3组患者肠道清洁度、睡眠质量比较差异有统计学意义(P<0.05),不良反应发生率比较差异无统计学意义(P>0.05)。结论:手术当天给药2次能够显著提高患者肠道清洁度,同时能够降低失眠发生率,且安全性较高。
关键词 聚乙二醇;结肠镜检术;睡眠情况
Analysis of the Effects of Polyethylene Glycol on Patients′ Sleep and Intestinal Cleanliness At Different Time before Colonoscopy
WU Lishan
(First Hospital of Quanzhou,Quanzhou 362000,China)
Abstract Objective:To investigate the effects of PEG on the sleep and intestinal cleanliness of patients before and after colonoscopy.Methods:Choose in June 2018 to March 2019 in our hospital 93 cases of patients as the research object,and randomly divided into A,B,C three groups,A group of patients with preoperative 1 d 16:00 on the day of surgery and 10:00 every large dose once; Group B patients with preoperative 1 d at 19:00 10:00 the delivery time,and on the day of surgery patients of group C-11:00 at 6:00 on the day of surgery for twice,the comparative analysis of three groups after dosing the intestinal cleanliness,preoperative 1 d night sleep quality and incidence of adverse reactions.Results:There were significant differences in intestinal cleanliness and sleep quality between the three groups(P<0.05).There was no significant difference in the incidence of adverse reactions(P>0.05).Conclusion:Administration twice a day on the day of surgery can significantly improve the cleanliness of the intestines,while reducing the incidence of insomnia,and the safety is higher.
Keywords Polyethylene glycol;Colonoscopy; Sleep
中图分类号:R338.63文献标识码:Adoi:10.3969/j.issn.2095-7130.2020.02.010
结肠镜检查是临床上常用的检查方式,能够通过肛门插入逆行的方式依次对直肠、乙状结肠、降结肠、横结肠、升结肠等部位进行镜检。聚乙二醇是一类水溶性较好的聚合物,具有无毒、无刺激性等优点,能够通过增加粪便含水量的方式改变肠道电解质浓度,达到快速清理肠道粪便的效果[1]。但临床实践发现,服用聚乙二醇会导致患者出现急性腹泻,降低其晚间睡眠质量,存在影响结肠镜检的隐患,因而如何在提高肠道清洁度的同时最大程度降低对患者睡眠质量的影响,成为医务工作者研究的重要。本文作者通过研究发现,手术当天给药两次能够显著提高患者肠道清洁度,同时能够降低失眠发生率,且安全性较高,现报道如下。……
