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阿奇霉素治疗小儿支原体肺炎的效果评价

2020-08-09谭丰瑜

中外医疗 2020年15期
关键词:阿奇霉素小儿

谭丰瑜

[摘要] 目的 研究阿奇霉素对小儿支原体肺炎的治疗效果。方法 方便选取该院于2017年3月—2018年1月期间收治的90例小儿支原体肺炎患者,通过区组随机化法将患者划分成对照组和研究组,各45例,分别使用红霉素和阿奇霉素进行治疗,对两组治疗效果进行研究分析。结果 研究组治疗有效率(95.55%)高于对照组(82.22%),差异有统计学意义(χ2=4.050,P=0.044);不良反应发生率(8.89%)低于对照组(26.67%),差异有统计学意义(χ2=4.865,P=0.027);研究组咳嗽消失时间、肺部啰音消失时间、肺部阴影消失时间、退热时间、喘息时间、住院时间分别为(9.62±0.98)、(9.26±2.22)、(12.26±2.22)、(8.50±1.35)、(2.22±1.01)、(13.34±2.01)d,對照组咳嗽消失时间、肺部啰音消失时间、肺部阴影消失时间、退热时间、喘息时间、住院时间分别为(15.38±1.94)、(13.89±2.55)、(16.25±2.44)、(13.45±1.86)、(5.13±2.04)、(17.64±2.16)d其数据与对照组相比较差异有统计学意义(t=17.778,P=0.000;t=9.186,P=0.000;t=8.114,P=0.000;t=14.448,P=0.000;t=8.670,P=0.000;t=9.776,P=0.000)。结论 为小儿支原体肺炎患者使用阿奇霉素进行治疗,效果显著,生活质量评分得到提升,有利于病情恢复,值得大力推广。

[关键词] 阿奇霉素;小儿;支原体;肺炎;红霉素

[Abstract] Objective To study the effect of azithromycin on mycoplasma pneumonia in children. Methods Ninety patients with mycoplasma pneumonia in the hospital between March 2017 and January 2018 were conveniently selected, and the patients were divided into control group and study group by block randomization method. The number of cases in each group was 45. Erythromycin and azithromycin were used for treatment, and the treatment effects of the two groups were analyzed. Results The treatment group's effective rate (95.55%) was higher than that of the control group (82.22%), and the difference was significant (χ2=4.050, P=0.044). The incidence of adverse reactions (8.89%) was lower than that of the control group (26.67%), and the difference was significant(χ2=4.865, P=0.027); cough disappearance time, lung murmur disappearance time, lung shadow disappearance time, antipyretic time, wheezing time, and hospital stay were (9.62 ± 0.98) d, (9.26 ± 2.22)d, (12.26 ± 2.22) d, (8.50 ± 1.35) d, (2.22±1.01) d, (13.34 ± 2.01) d, cough disappearance time, lung murmur disappearance time, lung shadow disappearance time in the control group, antipyretic time, wheezing time, and hospitalization time were (15.38 ± 1.94) d, (13.89 ± 2.55) d, (16.25 ± 2.44) d, (13.45 ± 1.86) d, (5.13±2.04) d, (17.64 ± 2.16) d. There was a significant difference between the data and the control group (t=17.778,P=0.000;t=9.186,P=0.000;t=8.114,P=0.000;t=14.448,P=0.000;t=8.670,P=0.000;t=9.776,P=0.000). Conclusion The use of azithromycin in the treatment of children with mycoplasmal pneumonia has a significant effect, and the quality of life score is improved, which is conducive to the recovery of the disease and is worthy of vigorous promotion.

[Key words] Azithromycin; Children; Mycoplasma; Pneumonia; Erythromycin

在对例体造成感染的支原体类型中,肺炎支原体属于呼吸道感染的关键因子,它是一种没有细胞壁、原核细胞类型的一种微生物有机体,形状为圆形、条形、或分枝状,非常容易粘附在呼吸道黏膜表面,对例体造成感染,尤其对于儿童和年轻群体来讲,更容易受到感染[1]。支原体肺炎属于比较普遍的呼吸道病原菌,会引发轻度上呼吸道感染,乃至非典型肺炎等不同程度和类型的疾病[2]。小儿支原体肺炎的临床表现为头疼、无力、发烧、咳嗽等,临床对该病症的治疗,主要以药物治疗为主[3]。……

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