赵丽明

[摘要] 目的 探討补肾活血周期疗法治疗子宫内膜异位症（EMT）不孕的临床效果与安全性。 方法 方便选择2013年8月—2015年10月该院收治的64例EMT不孕患者，将其随机分为观察组与对照组，每组32例，两组均给予常规治疗，对照组术后不作其他治疗，观察组在排卵期、排卵后分别采用相应补肾活血药物进行周期治疗，对比两组治疗前后子宫内膜厚度、子宫类型及妊娠结局。 结果 经阴道多普勒超声检查显示观察组治疗后子宫内膜厚度（9.69±0.88）mm明显高于对照组（6.75±0.75）mm，差异有统计学意义（t=8.959，P<0.05），且观察组子宫内膜类型以A型、B型为主，较治疗前明显改善，与对照组比较差异有统计学意义（P<0.05）。观察组1年随访期内成功妊娠率为56.25%，明显高于对照组的34.38%，差异有统计学意义（χ2=11.473，P<0.05）。结论 补肾活血周期疗法治疗子宫内膜异位症能够有效改善子宫内膜情况，提高妊娠率，值得临床推广。

[关键词] 子宫内膜异位症;不孕症;补肾活血周期疗法;临床疗效

[中图分类号] R271.14          [文献标识码] A          [文章编号] 1674-0742（2018）08（c）-0169-03

Analysis of the Effect of Bushen Huoxue Cycling Therapy on Infertility of Endometriosis

ZHAO Li-ming

Department of Traditional Chinese Medicine， People's Hospital of Pu'er， Pu'er， Yunnan Province， 665000 China

[Abstract] Objective To investigate the clinical efficacy and safety of Bushen Huoxue Cycling Therapy for endometriosis （EMT） infertility. Methods 64 infertile EMT patients admitted to the hospital from August 2013 to October 2015 were convenient selected and randomly divided into observation group and control group， with 32 cases in each group. Both groups were given conventional treatment. Control group without any other treatment， the observation group was treated with the appropriate kidney and blood circulation drugs respectively during the ovulation period and after ovulation， and the endometrial thickness， uterine type， and pregnancy outcome before and after treatment were compared. Results Transvaginal Doppler ultrasonography showed that the endometrial thickness （9.69±0.88） mm in the observation group was significantly higher than that in the control group （6.75±0.75） mm， with the difference was statiatically signficant（t=8.959， P<0.05）， and the observation group endometrium type A， B-type， significantly improved than before treatment， compared with the control group， the difference was statistically significant （P<0.05）. In the observation group， the successful pregnancy rate was 56.25% during the 1-year follow-up period， which was significantly higher than the 34.38% of the control group. The difference between the groups was statistically significant （χ2=11.473， P<0.05）. Conclusion Bushenhuoxue cycle therapy for endometriosis can effectively improve the endometrium and improve the pregnancy rate. It is worthy of clinical promotion.

[Key words] Endometriosis; Infertility; Bushenhuoxue cycle therapy; Clinical efficacy

子宫内膜异位症（EMT）不孕是妇科常见疾病，指子宫内膜组织离开子宫腔在其他部位生长所引起的不孕症，常见病因包括黄体功能不全、自身免疫反应等，临床症状以不孕、盆腔疼痛、痛经等为主[1]。现阶段采用药物治疗虽能有效抑制排卵，但是会影响自然妊娠，对改善妊娠率不利[2]。国内众多中医学者认为EMT不孕的病机为肾虚、血瘀，故该病治疗应当以补肾活血为大法，并临证化裁。该院于2013年8月—2015年10月对64例EMT不孕患者分别应用补肾活血周期疗法与常规方法进行干预，获得了满意效果，现报道如下。

1  资料与方法

1.1  一般资料

方便选择在该院妇科接受治疗的64例EMT不孕患者，将符合诊断与选择标准的64例患者按照治疗方法不同随机分为观察组与对照组，每组32例，观察组患者年龄为24～39岁，平均年龄（31.40±4.22）岁，体重指数（23.41±2.65）kg/m2，病程13～57个月，平均病程（25.39±6.97）个月，病理分型：原发性不孕19例（59.38%），继发性不孕13例（40.63%）。……