头孢哌酮与左氧氟沙星治疗老年支气管扩张急性加重患者的临床观察
2018-03-31张红霞张斌董建强
张红霞 张斌 董建强
【摘要】目的 针对老年支气管扩张急性加重患者的诊疗现状,对比头孢哌酮与左氧氟沙星的治疗效果。方法 选取2015年1月~2016年12月我院进行治疗的老年支气管扩张急性加重患者88例。将其随机分为两组,观察组44例,采用头孢哌酮治疗,对照组44例,采用左氧氟沙星治疗,对比两组患者的治疗效果。结果 治疗后,两组患者的白细胞水平和中胜粒细胞百分比等指标明显改善,其中觀察组的改善情况更加良好(P<0.05);观察组患者总有效率95.45%高于对照组77.27%且不良反应率2.27%低于对照组18.18%(P<0.05)。结论 与左氧氟沙星治疗方案对比,头孢哌酮的临床效果更加显著,不良反应更少,可以作为老年支气管扩张急性加重患者治疗的首选药物。
【关键词】头孢哌酮;左氧氟沙星;支气管扩张;急性加重期
【中图分类号】R562 【文献标识码】A 【文章编号】ISSN.2095-6681.2017.29..02
【Abstract】Objective In view of the elderly patients with acute exacerbation of bronchiectasis and treatment status quo, compared with levofloxacin cefoperazone treatment effect.Methods Selected in January 2015-December 2016, to the hospital for treatment of 88 cases of elderly patients with bronchiectasis exacerbations.Patients were randomly divided into two groups,44 cases of observation group, treated with cefoperazone, control group treated by levofloxacin, 44 cases were contrast the treatment effect of two groups of patients.Results After treatment, two groups of victory in the patient's level of white blood cells and granulocyte percentage and other indicators improved significantly, including the improvement of the observation group is better (P<0.05);Observation group of patients with total effective rate (95.45%) than the control group (77.27%) and adverse reaction rate (2.27%) is lower than the control group (18.18%) (P<0.05).Conclusion Compared with levofloxacin treatment, the clinical effect of cefoperazone even more significant, less adverse reaction, can be used as a drug of choice for treatment in elderly patients with bronchiectasis exacerbations.
【Key words】Cefoperazone;Levofloxacin;Bronchiectasis;Acute exacerbation period
支气管扩张急性加重期主要临床表现为咳嗽、咯血等,早期的治疗和干预能够减少急性加重次数,控制病情进展[1]。目前,临床上主要采用头孢哌酮与左氧氟沙星进行治疗,本文将选取到我院进行治疗的老年支气管扩张急性加重患者88例,观察其治疗效果,现报道如下。
1 资料与方法
1.1 一般资料
选取2015年1月~2016年12月我院进行治疗的老年支气管扩张急性加重患者88例。所有患者均已经过诊断,符合支气管扩张急性加重诊断标准。将患者随机分为两组,观察组44例,女性18例,男性26例,平均年龄(67.10±7.18)岁。对照组44例,女性19例,男性25例,平均年龄(67.55±7.27)岁。排除标准:①本次研究药物(头孢哌酮、左氧氟沙星)过敏患者;②依从性较差,未能完成治疗患者;③呼吸衰竭或心力衰竭患者;④其他肺部或支气管疾病引起的咳嗽、咯血患者等。
1.2 方法
所有患者均采取常规吸氧、平喘、补液、心电监护等治疗,对照组患者采用左氧氟沙星治疗,生产厂家:扬子江药业集团;……
