罗爱国

[摘要] 目的 分析持续皮下注射胰岛素治疗糖尿病合并脑卒中临床效果。 方法 选取2012年4月～2015年6月我院收治的156例糖尿病合并脑卒中患者作为研究对象，按照随机数字表法分为参照组（予以胰岛素多次皮下注射治疗）和观察组（予以胰岛素泵持续皮下注射治疗），各78例，比较两组临床治疗效果。 结果 观察组并发症发生率明显低于参照组，差异有统计学意义（P<0.05）；两组治疗2周后NIHSS评分进行比较，组间差异有统计学意义（P<0.05）；两组患者治疗期间血糖达标时间、低血糖发生率以及血糖平均值比较，差异具有统计学意义（P<0.05）。 结论 持续皮下注射胰岛素治疗糖尿病合并脑卒中临床疗效显著，安全性高，值得临床使用，具有积极的推广价值。

[关键词] 脑卒中；糖尿病；持续皮下注射胰岛素

[中图分类号] R587.1 [文献标识码] A [文章编号] 2095-0616（2017）11-245-03

Clinical analysis on continuous subcutaneous insulin injection in treatment of diabetes complicated with cerebral stroke

LUO Aiguo

Bao'an District Central Hospital of Shenzhen，Shenzhen 518128，China

[Abstract] Objective To analyze clinical effect of continuous subcutaneous insulin injection in treatment of diabetes complicated with cerebral stroke. Methods 156 patients with diabetes complicated with cerebral stroke who were admitted to our hospital from April 2012 to June 2015 were selected as research objects.According to lottery method，they were divided into the reference group（treated by multiple subcutaneous insulin injection） and the observation group（continuous subcutaneous insulin injection），with 78 in each.Clinical curative effects of two groups were compared. Results Complication rate of the observation group was significantly lower than that of the control group.The difference was statistically significant（P<0.05）.Difference in NIHSS score of 2 weeks after treatment in two groups had statistical significance（P<0.05）.During treatment，differences in time for reaching standard of blood glucose，incidence of hypoglycemia and mean value of blood glucose of patients in two groups had statistical significance （P<0.05）. Conclusion Continuous subcutaneous insulin injection in treatment of diabetes complicated with cerebral stroke has a significant clinical curative effect.It is safe，which is worthy of clinical application.In addition，it is of positive value of promotion.

[Key words] Cerebral stroke；Diabetes；Continuous subcutaneous insulin injection

糖尿病是临床内分泌代谢系统发病率较高的一种疾病类型，因其需要终身治疗，故对患者身心健康和生活质量带来了严重威胁[1]。糖尿病患者很容易合并脑卒中情况，当脑卒中处于急性发作期的应激反应状态时就会加重糖尿病患者的病情，临床之中不仅需要对患者血糖进行控制，还要统筹兼顾脑卒中的治疗[2]，但是目前对胰岛素的具体给药途径尚未明确，这在一定程度上增加了临床治疗的难度[3]。本文选取我院收治的156例糖尿病合并腦卒中患者作为研究对象，对不同给药途径的临床治疗效果进行分析，现报道如下。

1 资料与方法

1.1 一般资料

选取2012年4月～2015年6月我院收治的156例糖尿病合并脑卒中患者作为研究对象，所有患者均符合世界卫生组织制定的糖尿病临床诊断标准[3]，且同时合并脑卒中的情况。本组研究中排除脑肿瘤、癫痫以及脑炎等患者。156例患者中男74例，女82例，年龄56～79岁，平均（68.5±2.3）岁，病程2～9年，平均（5.6±1.2）年；……